potassium carbonate in toluene 20 h; Heating;

1: triphosgene / dimethylsulfoxide 2: 31 percent View Scheme

1: 81 percent / zinc, HCl / acetic acid 2: 92 percent / tetrahydrofuran / 48 h / Ambient temperature 3: 100 percent / sodium periodate / methanol; H2O / 19 h / Ambient temperature 4: 53 percent / potassium carbonate / toluene / 20 h / Heating View Scheme

1: 82 percent / methylamine hydrochloride, K2CO3 / ethanol / 168 h / Ambient temperature 2: 81 percent / zinc, HCl / acetic acid 3: 92 percent / tetrahydrofuran / 48 h / Ambient temperature 4: 100 percent / sodium periodate / methanol; H2O / 19 h / Ambient temperature 5: 53 percent / potassium carbonate / toluene / 20 h / Heating View Scheme

1: 88 percent / TMSOTf / CCl4 / 0.5 h / Ambient temperature 2: AcOH / 2 h / 117 - 118 °C / various temp., time View Scheme

Streptomyces amakusaensis isotop labeling;

暂无反应条件数据

Yield given. Multistep reaction;

biosynthesis of labelled compound with Streptomyces amakusaensis; Mechanism;