2,2,-二甲基-2H-苯并吡喃合成路线 （共 66 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=130°C; 8 h;
参考文献
Kawase, Yoshiyuki; Yamaguchi, Seiji; Horita, Hisanori; Takeno, Junko; Kameyama, Hideaki
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 4 p. 1153 - 1155
反应条件
in diethyl ether; hexane
1 h; Ambient temperature; Yields of byproduct given;
参考文献
Alberola, Angel; Calvo, Blanca; Gonzalez-Ortega, Alfonso; Lopez, Cristina; Villafane, Fernando
Heterocycles, 1994 , vol. 38, # 4 p. 819 - 832
反应条件
toluene-4-sulfonic acid in toluene
36 h; Heating; Yield given;
参考文献
Aukrust, I.R.; Noushabadi, M.; Skatteboel, L.
Polish Journal of Chemistry, 1994 , vol. 68, # 11 p. 2167 - 2174
反应条件
1: 1) Na / 1) benzene, reflux, 4 h, 2) a) 0 deg C, 5 h, b) overnight
2: Ambient temperature; oxidation on air
View Scheme
参考文献
De Bernardi; Vidari; Vita Finzi; Fronza
Tetrahedron, 1992 , vol. 48, # 35 p. 7331 - 7344
反应条件
1: 1) Na / 1) benzene, reflux, 4 h, 2) a) 0 deg C, 5 h, b) overnight
2: Ambient temperature; oxidation on air
View Scheme
参考文献
De Bernardi; Vidari; Vita Finzi; Fronza
Tetrahedron, 1992 , vol. 48, # 35 p. 7331 - 7344
反应条件
n-butyllithium; water
1.) hexane, ether, RT, 1 h; Multistep reaction;
参考文献
Alberola, Angel; Calvo, Blanca; Gonzalez-Ortega, Alfonso; Lopez, Cristina; Villafane, Fernando
Heterocycles, 1994 , vol. 38, # 4 p. 819 - 832
反应条件
n-butyllithium
1.) Et2O, hexane, r.t., 45 min, 2.) Et2O, hexane; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Gabbutt; Hartley; Hepworth; Heron; Kanjia; Rahman
Tetrahedron, 1994 , vol. 50, # 8 p. 2507 - 2522
反应条件
1: iodine / 150 °C
2: N-bromo-succinimide; tetrachloromethane; dibenzoyl peroxide / Erwaermen des Reaktionsprodukts mit Natriumaethylat in Benzol
View Scheme
参考文献
Clemo; Ghatge
Journal of the Chemical Society, 1955 , p. 4347
反应条件
diethyl ether
Behandeln des Reaktionsprodukts mit verd. Schwefelsaeure;
参考文献
Houben
Chemische Berichte, 1904 , vol. 37, p. 496
反应条件
silica gel
1) ether, toluene, 38-40 deg C, 2 min; 2) toluene, 98 deg C, 8.5 h; Yield given. Multistep reaction;
参考文献
Strunz; Brillon; Giguere
Canadian Journal of Chemistry, 1983 , vol. 61, # 9 p. 1963 - 1964
