8-苯基-1,4-二氧杂螺[4.5]癸烷合成路线 （共 10 条）
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; P=2585.81 Torr; 2 h;
参考文献
Zhang, Xuqing; Hufnagel, Heather; Markotan, Thomas; Lanter, James; Cai, Chaozhong; Hou, Cuifen; Singer, Monica; Opas, Evan; McKenney, Sandra; Crysler, Carl; Johnson, Dana; Sui, Zhihua
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5577 - 5582
反应条件
Me2CH(OTMS); trimethylsilyl trifluoromethanesulfonate in dichloromethane T=-20°C; 3 h;
参考文献
Kurihara, Masaaki; Hakamata, Wataru
Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3413 - 3415
反应条件
diethyl ether; ammonia; sodium
参考文献
Horning et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 773
反应条件
1: ethylene glycol; toluene; benzenesulfonic acid / Entfernen des entstehenden Wassers 2: sodium; toluene; ethanol View Scheme
参考文献
Horning et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 773
反应条件
1: aqueous HCl; acetic acid 2: ethylene glycol; toluene; benzenesulfonic acid / Entfernen des entstehenden Wassers 3: sodium; toluene; ethanol View Scheme
参考文献
Horning et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 773
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,4-dioxane; water / 24 h / 100 °C / Inert atmosphere 2: palladium 10 on activated carbon; hydrogen / methanol / 2 h / 20 °C / 2585.81 Torr View Scheme
参考文献
Zhang, Xuqing; Hufnagel, Heather; Markotan, Thomas; Lanter, James; Cai, Chaozhong; Hou, Cuifen; Singer, Monica; Opas, Evan; McKenney, Sandra; Crysler, Carl; Johnson, Dana; Sui, Zhihua
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5577 - 5582
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,4-dioxane; water / 24 h / 100 °C / Inert atmosphere 2: palladium 10 on activated carbon; hydrogen / methanol / 2 h / 20 °C / 2585.81 Torr View Scheme
参考文献
Zhang, Xuqing; Hufnagel, Heather; Markotan, Thomas; Lanter, James; Cai, Chaozhong; Hou, Cuifen; Singer, Monica; Opas, Evan; McKenney, Sandra; Crysler, Carl; Johnson, Dana; Sui, Zhihua
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5577 - 5582
参考文献
Bergmann; Yaroslavsky
Journal of the American Chemical Society, 1950 , vol. 81, p. 2772,2774
参考文献
Horning et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 773
反应条件
2,6-dicarboxypyridinium chlorochromate in acetonitrile T=20°C; 0.266667 h;
参考文献
Lakouraj; Tajbakhsh; Khojasteh; Gholami
Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 12 p. 2645 - 2651
