5-己基呋喃-2(5H)-酮合成路线 （共 16 条）
反应条件
(PM,RS,RS)-i-Pr-SPRIX; palladium diacetate; p-benozquinone in 1,2-dichloro-ethane
T=30°C; 12 h; Inert atmosphere;
参考文献
Bajracharya, Gan B.; Koranne, Priti S.; Nadaf, Rashid N.; Gabr, Randa Kassem Mohamed; Takenaka, Kazuhiro; Takizawa, Shinobu; Sasai, Hiroaki
Chemical Communications, 2010 , vol. 46, # 47 p. 9064 - 9066
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane
T=0°C;
参考文献
Nokami, Junzo; Ogawa, Hideki; Miyamoto, Shinya; Mandai, Tadakatsu; Wakabayahi, Shoji; Tsuji, Jiro
Tetrahedron Letters, 1988 , vol. 29, # 40 p. 5181 - 5184
反应条件
in neat (no solvent)
T=120°C; P=0.05 - 0.1 Torr; 2 h;
参考文献
Pohmakotr, Manat; Jarupan, Prapanpong
Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2253 - 2256
反应条件
triethylamine in chloroform
Ambient temperature;
参考文献
Tanikaga, Rikuhei; Nozaki, Yoshihito; Tanaka, Kazuhiko; Kaji, Aritsune
Chemistry Letters, 1982 , p. 1703 - 1706
反应条件
1: 69 percent / tetrahydrofuran / 3.5 h / -78 - -10 °C
2: aq. HCl / dioxane / Heating
3: triethylamine / CHCl3 / Ambient temperature
View Scheme
参考文献
Tanaka, Kazuhiko; Wakita, Hisanori; Yoda, Hidemi; Kaji, Aritsune
Chemistry Letters, 1984 , p. 1359 - 1362
反应条件
1: tetrahydrofuran / -78 °C
2: pyridine
3: NaIO4 / methanol; H2O
4: 1.) LDA; 2.) glacial acetic acid / 1.) THF, -78 to RT, 10 h; 2.) THF, RT, 1 h
5: 76 percent / neat (no solvent) / 2 h / 120 °C / 0.05 - 0.1 Torr
View Scheme
参考文献
Pohmakotr, Manat; Jarupan, Prapanpong
Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2253 - 2256
反应条件
1: pyridine
2: NaIO4 / methanol; H2O
3: 1.) LDA; 2.) glacial acetic acid / 1.) THF, -78 to RT, 10 h; 2.) THF, RT, 1 h
4: 76 percent / neat (no solvent) / 2 h / 120 °C / 0.05 - 0.1 Torr
View Scheme
参考文献
Pohmakotr, Manat; Jarupan, Prapanpong
Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2253 - 2256
反应条件
1: 1.) LDA; 2.) glacial acetic acid / 1.) THF, -78 to RT, 10 h; 2.) THF, RT, 1 h
2: 76 percent / neat (no solvent) / 2 h / 120 °C / 0.05 - 0.1 Torr
View Scheme
参考文献
Pohmakotr, Manat; Jarupan, Prapanpong
Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2253 - 2256
反应条件
1: 82 percent / PdCl2, p-benzoquinone / 12 h / 40 °C
2: 89 percent / CrO3/H2SO4 / acetone / 0 °C
3: 92 percent / DBU / CH2Cl2 / 0 °C
View Scheme
参考文献
Nokami, Junzo; Ogawa, Hideki; Miyamoto, Shinya; Mandai, Tadakatsu; Wakabayahi, Shoji; Tsuji, Jiro
Tetrahedron Letters, 1988 , vol. 29, # 40 p. 5181 - 5184
反应条件
1: 89 percent / CrO3/H2SO4 / acetone / 0 °C
2: 92 percent / DBU / CH2Cl2 / 0 °C
View Scheme
参考文献
Nokami, Junzo; Ogawa, Hideki; Miyamoto, Shinya; Mandai, Tadakatsu; Wakabayahi, Shoji; Tsuji, Jiro
Tetrahedron Letters, 1988 , vol. 29, # 40 p. 5181 - 5184
