1: 90 percent / hydrogen peroxide, potassium hydroxide / methanol; H2O / 1 h / 15 °C 2: 7.8 g / tosyl hydrazine / acetic acid; CH2Cl2 / 8 h / Ambient temperature 3: 2.2 g / tetrahydrofuran / 3 h / Ambient temperature 4: 1.62 g / pyridine-chromic anhydride complex / CH2Cl2 / 0.25 h / Ambient temperature 5: 1.6 g / hydrogen, pyridine / 10percent Pd-BaSO4 / ethyl acetate View Scheme

hydroxocobalamine hydrochloride; lithium perchlorate; NH4Br in N,N-dimethyl-formamide T=20°C; electrolysis;

bis(cyclopentadienyl)zirconium dihydride; nickel dichloride T=150°C; 8 h;

1: 93 percent / NaI / acetone / Ambient temperature View Scheme

1: 3N HCl / tetrahydrofuran / 0.25 h / 0 °C 2: p-TsOH / benzene 3: 79 percent / sodium hexamethyldisilazane / tetrahydrofuran / 1.5 h / 40 °C 4: 1.) 3N HCl, 2.) 0.5percent NaOH / 1.) THF, 0deg C, 1 h, 2.) ether, 0 deg C, 1 min 5: 72 percent / lithium di-n-butylcuprate / diethyl ether / -78 °C View Scheme

1: 79 percent / sodium hexamethyldisilazane / tetrahydrofuran / 1.5 h / 40 °C 2: 1.) 3N HCl, 2.) 0.5percent NaOH / 1.) THF, 0deg C, 1 h, 2.) ether, 0 deg C, 1 min 3: 72 percent / lithium di-n-butylcuprate / diethyl ether / -78 °C View Scheme

1: 1.) 3N HCl, 2.) 0.5percent NaOH / 1.) THF, 0deg C, 1 h, 2.) ether, 0 deg C, 1 min 2: 72 percent / lithium di-n-butylcuprate / diethyl ether / -78 °C View Scheme

sulfuric acid in methanol; water 1 h; Ambient temperature; Yield given;

1: potassium, liquid ammonia, FeCl3 / 0.17 h 2: aq. 10percent H2SO4 / methanol; H2O / 1 h / Ambient temperature View Scheme

1: potassium, liquid ammonia, FeCl3 / 0.17 h 2: aq. 10percent H2SO4 / methanol; H2O / 1 h / Ambient temperature View Scheme