1,4-环己烷双(甲基胺)合成路线 （共 7 条）
反应条件
ammonia; 4,5-bis(dicyclohexylphosphinomethyl)acridine in tetrahydrofuran T=155°C; P=34128.4 Torr; 12 h; AutoclaveInert atmosphere;
参考文献
US2012/232293 A1, ;
Page/Page column 12; 16 ;
反应条件
1: With ammonia in methanol T=100°C; 0.666667 - 0.75 h; 2: With hydrogen; Ni catalyst supported on silica/alumina in methanol T=100°C; P=41372.9 Torr; 5 h; Product distribution / selectivity;
参考文献
DOW GLOBAL TECHNOLOGIES, INC.
Patent: WO2007/5594 A2, 2007 ;
Location in patent: Page/Page column 18-19 ;
反应条件
ammonia; α-n-hexadecene in 1,4-dioxane
反应条件
ammonia; hydrogen; Ni-5256W in methanol T=130°C; P=15514.9 - 51716.2 Torr; 5 h; Product distribution / selectivity;
参考文献
WO2007/5594 A2, ;
Page/Page column 14-16 ;
反应条件
ammonia; hydrogen; Cu#Ni#Cr T=180 - 210°C; P=130050 Torr; Product distribution / selectivity;
参考文献
WO2009/114438 A2, ;
Page/Page column 4-6 ;
反应条件
hydrazine hydrate in ethanol 4 h; Reflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 63, p. 907 - 923
反应条件
(i) ClCO2Et, Et3N, (ii) /BRN= 2071383/; Multistep reaction;
参考文献
Bayer AG
Patent: DE2515146 , 1976 ;
Chem.Abstr., 1977 , vol. 86, # 71947
