1: pyridine 2: palladium; acetic acid / Hydrogenation 3: acetic acid; sodium nitrite; sulfuric acid; aqueous potassium iodide solution View Scheme

potassium hydroxide T=150°C;

1: 84.6 percent / copper powder / xylene / Heating; 1.) 2 h, 2.) 1 h 2: 85 percent / 1.) 96percent H2SO4, 2.) H2O / 1.) 70 deg C, 2.) 95 deg C, 1h 3: 1.) oleum (20percent SO3), 2.) sodium azide 4: 23.4 percent / HNO3, H2SO4 / 1.) 30-35 deg C, 1.5 h, 2.) 65 deg C, 30 min, 3.) 70 deg C, 1.5 h 5: 38.6 percent / oleum (30percent SO3), H2O2 / 1.) 8-12 deg C, 1 h, 2.) 14 d, 25 deg C View Scheme