N,O-双(三甲基硅烷基)三氟乙酰胺合成路线 （共 118 条）
反应条件
1: methyl vinyl ketone With HCo(CO)4 in dichloromethane
T=-40°C; Reduction;
2: N,O-bis(trimethylsilyl) trifluoroacetamide in dichloromethane
T=-30°C; silylation;
参考文献
Sisak, Attila
Journal of Organometallic Chemistry, 1999 , vol. 586, # 1 p. 48 - 53
反应条件
1: 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-propane-1,3-diol With α,α'-azodiizobutyramidine-dihydrochloride; H218O in acetone
T=60°C; pH=5; 3 h; Inert atmosphereSodium acetate buffer;
2: N,O-bis(trimethylsilyl) trifluoroacetamide With pyridine
T=60°C; 1 h;
参考文献
Ohashi, Yasunori; Uno, Yukiko; Amirta, Rudianto; Watanebe, Takahito; Honda, Yoichi; Watanabe, Takashi
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2481 - 2491
反应条件
1: 1-(4-ethoxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-propane-1,3-diol With water; α,α'-azodiizobutyramidine-dihydrochloride in acetone
T=60°C; pH=5; 3 h; Inert atmosphereSodium acetate buffer;
2: N,O-bis(trimethylsilyl) trifluoroacetamide With pyridine
T=60°C; 1 h;
参考文献
Ohashi, Yasunori; Uno, Yukiko; Amirta, Rudianto; Watanebe, Takahito; Honda, Yoichi; Watanabe, Takashi
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2481 - 2491
反应条件
in acetonitrile
0.333333 h; Ambient temperature;
参考文献
Wysocki Jr.; Siddiqui; Barchi Jr.; Driscoll; Marquez
Synthesis, 1991 , # 11 p. 1005 - 1008
参考文献
Netscher, Thomas; Strauss, Christian
Liebigs Annalen der Chemie, 1987 , p. 259 - 261
反应条件
in acetonitrile
0.5 h; Ambient temperature;
参考文献
Horvat, Robert J.; Senter, Samuel D.
Organic Mass Spectrometry, 1983 , vol. 18, # 10 p. 413 - 417
反应条件
sodium perchlorate
1.) CH3CN, H2O, electrolysis, 2.) ether, 60 deg C, 24 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Hall, Larry R.; Iwamoto, Reynold T.; Hanzlik, Robert P.
Journal of Organic Chemistry, 1989 , vol. 54, # 10 p. 2446 - 2451
反应条件
in acetonitrile
0.5 h; Ambient temperature;
参考文献
Kotowska, Urszula; Isidorov, Valery A.
Central European Journal of Chemistry, 2011 , vol. 9, # 5 p. 813 - 824
反应条件
in acetonitrile
0.5 h; Ambient temperature;
参考文献
Kotowska, Urszula; Isidorov, Valery A.
Central European Journal of Chemistry, 2011 , vol. 9, # 5 p. 813 - 824
反应条件
in hexane; dichloromethane
T=60°C; Substitution; 0.666667 h;
参考文献
Yu, Jianzhen; Flagan, Richard C.; Seinfeld, John H.
Environmental Science and Technology, 1998 , vol. 32, # 16 p. 2357 - 2370
