1: diethyl carboxymethylphosphonate With n-butyllithium in tetrahydrofuran T=-65°C; 0.75 h; 2: phenylpropargyl aldehyde in tetrahydrofuran T=-65 - 20°C; 3: With hydrogenchloride in tetrahydrofuran; water pH=1.0;
参考文献
ERRANT GENE THERAPEUTICS, INC.
Patent: WO2006/52916 A2, 2006 ;
Location in patent: Page/Page column 18 ;
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