4-二甲胺基吡啶N-氧化物合成路线 （共 32 条）
反应条件
1: HNO3; H2SO4 / 160 °C 2: AcOH; Fe / Heating 3: HNO3; H2SO4 / 20 °C 4: H2SO4 / 100 °C 5: 51 percent / Fe / 2 h / Heating 6: aq. NaOH / Heating View Scheme
参考文献
Seley, Katherine L.; O'Daniel, Peter I.; Salima, Samer
Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 12 p. 2133 - 2144
反应条件
1: HNO3; H2SO4 / 160 °C 2: AcOH; Fe / Heating View Scheme
参考文献
Xuanzhu Pharma Co., Ltd.
Patent: US2012/289497 A1, 2012 ;
反应条件
chiral ruthenium porphyrin complex catalyst in toluene T=-10°C; 48 h; Title compound not separated from byproducts.;
参考文献
Gross, Zeev; Ini, Santiago
Organic Letters, 1999 , vol. 1, # 13 p. 2077 - 2080
反应条件
copper(l) iodide; zinc in ethanol T=55 - 60°C; 3 h;
参考文献
Singh, Sunil Kumar; Srinivasa Reddy; Mangle, Mangesh; Ravi Ganesh
Tetrahedron, 2007 , vol. 63, # 1 p. 126 - 130
反应条件
trichlorophosphate 4 h; Heating;
参考文献
Kaneko, Chikara; Uchiyama, Keiji; Sato, Masayuki; Katagiri, Nobuya
Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, # 9 p. 3658 - 3671
反应条件
1: HNO3; H2SO4 / 160 °C 2: AcOH; Fe / Heating 3: HNO3; H2SO4 / 20 °C 4: H2SO4 / 100 °C 5: 51 percent / Fe / 2 h / Heating 6: aq. NaOH / Heating 7: 96 percent / Ac2O / 4.5 h / Heating View Scheme
参考文献
Seley, Katherine L.; O'Daniel, Peter I.; Salima, Samer
Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 12 p. 2133 - 2144
反应条件
chiral ruthenium porphyrin complex catalyst in toluene T=-10°C; 48 h; Title compound not separated from byproducts.;
参考文献
Gross, Zeev; Ini, Santiago
Organic Letters, 1999 , vol. 1, # 13 p. 2077 - 2080
反应条件
2-methyl-but-2-ene; Ru(VI)(TMP)O2 in benzene T=30°C; 15 h;
参考文献
Nakagawa, Hiroshi; Higuchi, Tsunehiko; Kikuchi, Kazuya; Urano, Yasuteru; Nagano, Tetsuo
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 10 p. 1656 - 1657
反应条件
copper(l) iodide; zinc in ethanol T=55 - 60°C; 3 h;
参考文献
Singh, Sunil Kumar; Srinivasa Reddy; Mangle, Mangesh; Ravi Ganesh
Tetrahedron, 2007 , vol. 63, # 1 p. 126 - 130
反应条件
chiral ruthenium porphyrin complex catalyst in toluene T=-10°C; 48 h; Title compound not separated from byproducts.;
参考文献
Gross, Zeev; Ini, Santiago
Organic Letters, 1999 , vol. 1, # 13 p. 2077 - 2080
