zinc(II) chloride T=60 - 80°C; 12 h;

silica gel-supported lanthanum(III) oxide T=120°C; 5 h; AutoclaveInert atmosphere;

1: pentanoic acid[2,6-diethyl-2,3,6-trimethyl-1-(1-phenyl-ethoxy)-piperidin-4-yl]-amide With trichloroisocyanuric acid; 1,8-diazabicyclo[5.4.0]undec-7-ene T=20°C; Hofmann rearrangement; Inert atmosphere; 2: methanol T=65°C; Hofmann rearrangement; Inert atmosphere;

nitrogen in tetrahydrofuran byproducts: CuCl; Pd-compd. in THF and CuCl2(BuNH2)2 in a Cu/Pd molar ratio of 4:1 are loaded sep. in the 2 branches of an inverted-Y glass reactor. Reactor is closed under N2, contents are mixed and stirred for 1 h.; IR, GC-MS and GLC anal. of liq. phase shows presence of BuNH2COOCH3. Filtn. of solid residue (anaerobic conditions), sepn. of PdCl2(bipy) from CuCl by addn. of MeOH soln. contg. bipy, IR, elem. anal. Removal of MeOH(vac.) gives CuCl(bipy). Elem. anal.;

triethylamine 22 h; Reflux;

oxygen; alkali metal halide; platinum group metal Heatingpressure;

bromine 1.) 5 deg C, 0.5 h, 2.) RT, 5 h;

in ethanol T=18 - 25°C; 24 h;

potassium tert-butylate T=60°C; 0.0833333 h;

n-butyllithium; water; ammonium chloride 1.) THF, hexane, -80 gradC to -30 gradC, 1h 2.) -80 gradC to -20 gradC; Yield given. Multistep reaction;