3-(哌啶-1-基磺酰)砒啶合成路线 （共 13 条）
反应条件
1: 3-iodo-pyridine With 1,10-phenanthroline; K2S2O5; tetrabutylammomium bromide; sodium formate; palladium diacetate; triphenylphosphine in dimethyl sulfoxide T=70°C; 2 h; Inert atmosphereMicrowave irradiation; 2: piperidine With N-bromosuccinmide in tetrahydrofuran; dimethyl sulfoxide T=0 - 23°C; 0.5 h; Inert atmosphere; chemoselective reaction;
参考文献
Shavnya, Andrei; Coffey, Steven B.; Smith, Aaron C.; Mascitti, Vincent
Organic Letters, 2013 , vol. 15, # 24 p. 6226 - 6229
反应条件
in N,N-dimethyl-formamide T=80°C; 48 h;
参考文献
Katritzky, Alan R.; Rodriguez-Garcia, Valerie; Nair, Satheesh K.
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 1849 - 1852
反应条件
1.1: SO2 / tetrahydrofuran / 1.25 h / -78 - 20 °C 1.2: 41 percent / Et3N / tetrahydrofuran / 10 h / 20 °C 2.1: 100 percent / dimethylformamide / 48 h / 80 °C View Scheme
参考文献
Katritzky, Alan R.; Rodriguez-Garcia, Valerie; Nair, Satheesh K.
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 1849 - 1852
反应条件
1: PCl5 / 3 h / Heating 2: benzene / 0.5 h / 0 °C View Scheme
参考文献
Breant, P.; Marsais, F.; Queguiner, G.
Synthesis, 1983 , # 10 p. 822 - 824
反应条件
in benzene T=0°C; 0.5 h; Yield given;
参考文献
Breant, P.; Marsais, F.; Queguiner, G.
Synthesis, 1983 , # 10 p. 822 - 824
反应条件
n-butyllithium; diisopropylamine
1.) Et2O, -70 deg C, 1 h; 2.) Et2O, -70 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Breant, P.; Marsais, F.; Queguiner, G.
Synthesis, 1983 , # 10 p. 822 - 824
反应条件
n-butyllithium; diisopropylamine
1.) Et2O, -70 deg C, 1 h; 2.) Et2O, -70 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Breant, P.; Marsais, F.; Queguiner, G.
Synthesis, 1983 , # 10 p. 822 - 824
反应条件
n-butyllithium; diisopropylamine
1.) Et2O, -70 deg C, 1 h; 2.) Et2O, -70 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Breant, P.; Marsais, F.; Queguiner, G.
Synthesis, 1983 , # 10 p. 822 - 824
反应条件
n-butyllithium; diisopropylamine
1.) Et2O, -70 deg C, 1 h; 2.) Et2O, -70 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Breant, P.; Marsais, F.; Queguiner, G.
Synthesis, 1983 , # 10 p. 822 - 824
反应条件
n-butyllithium; diisopropylamine
1.) Et2O, -70 deg C, 1 h; 2.) Et2O, -70 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Breant, P.; Marsais, F.; Queguiner, G.
Synthesis, 1983 , # 10 p. 822 - 824
