(4-氯苯基)(哌啶-1-基)甲酮合成路线 (共 26 条)
反应条件
dihydrogen peroxide; zirconium tetrachloride in ethanol; water T=25°C; 0.116667 h; chemoselective reaction;
参考文献
Bahrami, Kiumars; Khodaei, Mohammad Mehdi; Tirandaz, Yeganeh
Synthesis, 2009 , # 3 p. 369 - 371
反应条件
1: piperidine With C12H30NaO6(1+)*C56H84O4Sm(1-) in tetrahydrofuran 0.5 h; Inert atmosphere; 2: 4-chlorobenzaldehyde in tetrahydrofuran T=25°C; 3 h; Inert atmosphere;
参考文献
Li, Junmei; Xu, Fan; Zhang, Yong; Shen, Qi
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2575 - 2577
反应条件
N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine in dichloromethane T=20 - 25°C; 1.5 h;
参考文献
Cabre, Juan; Palomo, Antonio Luis
Synthesis, 1984 , # 5 p. 413 - 417
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
Xie, Weilong; Zhao, Mengdi; Cui, Chunming
Organometallics, 2013 , vol. 32, # 24 p. 7440 - 7444
反应条件
tert.-butylhydroperoxide; potassium carbonate in tetrahydrofuran T=80°C; 12 h; Sealed tube;
参考文献
Zhao, Qiong; Li, Hongji; Wang, Lei
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 39 p. 6772 - 6779
反应条件
Zr(NMe2)4 in toluene T=25°C; 10 h; Inert atmosphere;
参考文献
Stephenson, Nickeisha A.; Zhu, Jiang; Gellman, Samuel H.; Stahl, Shannon S.
Journal of the American Chemical Society, 2009 , vol. 131, # 29 p. 10003 - 10008
反应条件
sodium methylate in toluene T=50°C; 36 h; Inert atmosphere;
参考文献
Ohshima, Takashi; Hayashi, Yukiko; Agura, Kazushi; Fujii, Yuka; Yoshiyama, Asako; Mashima, Kazushi
Chemical Communications, 2012 , vol. 48, # 44 p. 5434 - 5436
反应条件
1: N-chloro-succinimide / acetonitrile / 3 h / 20 °C / |Inert atmosphere 2: copper (II) acetate monohydrate; tert.-butylhydroperoxide / 0.83 h / 82 °C / |Inert atmosphere View Scheme
参考文献
Vanjari, Rajeshwer; Guntreddi, Tirumaleswararao; Singh, Krishna Nand
Green Chemistry, 2014 , vol. 16, # 1 p. 351 - 356
反应条件
tert.-butylhydroperoxide; copper (II) acetate monohydrate T=82°C; Minisci Aromatic Substitution; 0.833333 h; Inert atmosphere;
参考文献
Cadoni, Roberta; Porcheddu, Andrea; Giacomelli, Giampaolo; De Luca, Lidia
Organic Letters, 2012 , vol. 14, # 19 p. 5014 - 5017,4
Title/Abstract Full Text Show Details
Cadoni, Roberta; Porcheddu, Andrea; Giacomelli, Giampaolo; De Luca, Lidia
Organic Letters, 2012 , vol. 14, # 19 p. 5014 - 5017
反应条件
in dichloromethane T=5°C; 0.333333 h;
参考文献
Ishihara, Hideharu; Muto, Shinya; Kato, Shinzi
Synthesis, 1986 , # 1 p. 128 - 130