(2-甲基-1H-吲哚-3-基)(苯基)甲酮合成路线 （共 30 条）
反应条件
1: 69 percent / TsOH / benzene / Heating
2: 36 percent / Et3N, P(2-CH3C6H4)3 / Pd(OAc)2 / dimethylformamide / 120 °C
View Scheme
参考文献
Sakamoto, Takao; Nagano, Tatsuo; Kondo, Yoshinori; Yamanaka, Hiroshi
Synthesis, 1990 , # 3 p. 215 - 218
反应条件
1: pyridinium chlorochromate / dichloromethane / 0 - 20 °C
2: sodium hydride / tetrahydrofuran
3: acetic acid; iron / 120 °C
View Scheme
参考文献
Coffman, Keith C.; Palazzo, Teresa A.; Hartley, Timothy P.; Fettinger, James C.; Tantillo, Dean J.; Kurth, Mark J.
Organic Letters, 2013 , vol. 15, # 8 p. 2062 - 2065
反应条件
1: sodium hydride / tetrahydrofuran
2: acetic acid; iron / 120 °C
View Scheme
参考文献
Coffman, Keith C.; Palazzo, Teresa A.; Hartley, Timothy P.; Fettinger, James C.; Tantillo, Dean J.; Kurth, Mark J.
Organic Letters, 2013 , vol. 15, # 8 p. 2062 - 2065
反应条件
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethyl sulfoxide / 72 h
2: pyridinium chlorochromate / dichloromethane / 0 - 20 °C
3: sodium hydride / tetrahydrofuran
4: acetic acid; iron / 120 °C
View Scheme
参考文献
Coffman, Keith C.; Palazzo, Teresa A.; Hartley, Timothy P.; Fettinger, James C.; Tantillo, Dean J.; Kurth, Mark J.
Organic Letters, 2013 , vol. 15, # 8 p. 2062 - 2065
反应条件
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethyl sulfoxide / 72 h
2: pyridinium chlorochromate / dichloromethane / 0 - 20 °C
3: sodium hydride / tetrahydrofuran
4: acetic acid; iron / 120 °C
View Scheme
参考文献
Coffman, Keith C.; Palazzo, Teresa A.; Hartley, Timothy P.; Fettinger, James C.; Tantillo, Dean J.; Kurth, Mark J.
Organic Letters, 2013 , vol. 15, # 8 p. 2062 - 2065
反应条件
5-sulfo salicylic acid in methanol
Heating;
参考文献
Akguen, Eyuep; Tunali, Mustafa; Pindur, Ulf
Archiv der Pharmazie (Weinheim, Germany), 1987 , vol. 320, # 5 p. 397 - 401
反应条件
1: 57 percent / CH2Cl2 / 1.) 0.5 h, -78 deg C; 2.) 1 h, RT
2: 41 percent / water / CH2Cl2 / 0.5 h
View Scheme
参考文献
Pindur, Ulf; Flo, Camran
Monatshefte fuer Chemie, 1986 , vol. 117, p. 375 - 384
反应条件
1: 86 percent / HBF4 / diethyl ether / -78 °C
2: 57 percent / CH2Cl2 / 1.) 0.5 h, -78 deg C; 2.) 1 h, RT
3: 41 percent / water / CH2Cl2 / 0.5 h
View Scheme
参考文献
Pindur, Ulf; Flo, Camran
Monatshefte fuer Chemie, 1986 , vol. 117, p. 375 - 384
反应条件
1: sulfosalicylic acid / Heating
2: 5.9 percent / sulfosalicylic acid / methanol / Heating
View Scheme
参考文献
Akguen, Eyuep; Tunali, Mustafa; Pindur, Ulf
Archiv der Pharmazie (Weinheim, Germany), 1987 , vol. 320, # 5 p. 397 - 401
反应条件
1: potassium carbonate / dimethyl sulfoxide / 80 - 90 °C
2: iron; acetic acid / 1 h / Reflux
View Scheme
参考文献
Janreddy, Donala; Kavala, Veerababurao; Bosco, J. W. John; Kuo, Chun-Wei; Yao, Ching-Fa
European Journal of Organic Chemistry, 2011 , # 12 p. 2360 - 2365
