(S)-(-)- α-甲基苄胺合成路线 （共 369 条）
反应条件
ωTA ATA-117 102907WW; Vibrio fluvialis Vf-ωTA 2100208MW; pyridoxal 5'-phosphate T=30°C; pH=7; 24 h; aq. phosphate buffer;
参考文献
Koszelewski, Dominik; Grischek, Barbara; Glueck, Silvia M.; Kroutil, Wolfgang; Faber, Kurt
Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 378 - 383
反应条件
L-threonine deaminase from Escherichia coli; recombinant (R)-selective ω-transaminase from Aspergillus terreus; pyridoxal 5'-phosphate T=37°C; pH=7.5; 5 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Malik, M. Shaheer; Park, Eul-Soo; Shin, Jong-Shik
Green Chemistry, 2012 , vol. 14, # 8 p. 2137 - 2140
反应条件
Candida antarctica lipase; 4 Angstroems MS in 1,4-dioxane T=30°C; 24 h; Product distribution;
参考文献
Sanchez, Victor M.; Rebolledo, Francisca; Gotor, Vicente
Journal of Organic Chemistry, 1999 , vol. 64, # 2-5 p. 1464 - 1470
反应条件
in dichloromethane T=-20°C; 2 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Al-Sehemi, Abdullah G.; Atkinson, Robert S.; Fawcett, John
Journal of the Chemical Society. Perkin Transactions 1, 2002 , vol. 2, # 2 p. 257 - 274
反应条件
1: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 3 h 2: hydroxylamine acetate / 40 °C View Scheme
参考文献
Yaozhong, Jiang; Peng, Guo; Guilan, Liu
Synthetic Communications, 1990 , vol. 20, # 1 p. 15 - 22
反应条件
in tetrahydrofuran T=-10°C; 12 h; Title compound not separated from byproducts.;
参考文献
Karnik, Anil V.; Kamath, Suchitra S.
Tetrahedron Asymmetry, 2008 , vol. 19, # 1 p. 45 - 48
反应条件
(S)-selective ω-transaminase from Ochrobactrum anthropi; pyridoxal 5'-phosphate T=37°C; pH=7.5; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Malik, M. Shaheer; Park, Eul-Soo; Shin, Jong-Shik
Green Chemistry, 2012 , vol. 14, # 8 p. 2137 - 2140
参考文献
Pope; Read
Journal of the Chemical Society, 1913 , vol. 103, p. 445
反应条件
sodium tetrahydroborate
参考文献
Lillis, Veronica; Kenna, James Mc; Kenna, Jean Mc; Smith, Martin J.; Taylor, Paul S.; Williams, Ian H.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 83 - 86
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Fernandez, Elena; Hooper, Mark W.; Knight, Frances I.; Brown, John M.
Chemical Communications, 1997 , # 2 p. 173 - 174
