(S)-(-)- α-甲基苄胺合成路线 (共 369 条)
反应条件
hydrogen; nickel in toluene T=70°C; P=75.0075 Torr; 24 h; Autoclave;
参考文献
Blacker, A. John; Stirling, Matthew J.; Page, Michael I.
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 642 - 648
反应条件
hydrogen; palladium-barium carbonate in toluene T=70°C; P=1500.15 Torr; 72 h;
参考文献
Parvulescu, Andrei N.; Jacobs, Pierre A.; De Vos, Dirk E.
Chemistry - A European Journal, 2007 , vol. 13, # 7 p. 2034 - 2043
反应条件
palladium T=50°C; rates of racemization; Ea; other temperature (100 deg C); Rate constantThermodynamic data;
参考文献
Roengpithya, Chayaporn; Patterson, Darrell A.; Livingston, Andrew G.; Taylor, Paul C.; Irwin, Jacob L.; Parrett, Mark R.
Chemical Communications, 2007 , # 33 p. 3462 - 3463
反应条件
hydrogen in toluene T=100°C; 1 h;
参考文献
Shakeri, Mozaffar; Tai, Cheuk-Wai; Goethelid, Emmanuelle; Oscarsson, Sven; Baeckvall, Jan-E.
Chemistry - A European Journal, 2011 , vol. 17, # 47 p. 13269 - 13273
参考文献
Uhan Corporation
Patent: US5990311 A1, 1999 ;
反应条件
in dimethyl sulfoxide T=50°C; 72 h;
参考文献
Couty, Francois; Evano, Gwilherm; Vargas-Sanchez, Monica; Bouzas, Gloria
Journal of Organic Chemistry, 2005 , vol. 70, # 22 p. 9028 - 9031
反应条件
in water 0.333333 h; Sonication;
参考文献
Aparicio, David M.; Teran, Joel L.; Roa, Luis F.; Gnecco, Dino; Juarez, Jorge R.; Orea, Maria L.; Mendoza, Angel; Flores-Alamo, Marcos; Micouin, Laurent
Synthesis, 2011 , # 14 art. no. M11511SS, p. 2310 - 2320
反应条件
1: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 81 percent / LAH / tetrahydrofuran / 64 h View Scheme
参考文献
Nelson, Todd D.; Rosen, Jonathan D.; Brands, Karel M.J.; Craig, Bridgette; Huffman, Mark A.; McNamara, James M.
Tetrahedron Letters, 2004 , vol. 45, # 48 p. 8917 - 8920
参考文献
Chan; Laughton; Queener; Stevens
Journal of Medicinal Chemistry, 2001 , vol. 44, # 16 p. 2555 - 2564
参考文献
Weidler; Bergson
Acta Chemica Scandinavica (1947-1973), 1964 , vol. 18, p. 1483,1485