(S)-(-)- α-甲基苄胺合成路线 (共 369 条)
反应条件
ammonium cerium(IV) nitrate; water in methanol T=0°C;
参考文献
Hoffmann, Sebastian; Seayad, Abdul Majeed; List, Benjamin
Angewandte Chemie - International Edition, 2005 , vol. 44, # 45 p. 7424 - 7427
反应条件
dimethylsulfide borane complex; enantiopure spiroborate ester in tetrahydrofuran T=25°C; 36 h; Title compound not separated from byproducts.;
参考文献
Huang, Xiaogen; Ortiz-Marciales, Margarita; Huang, Kun; Stepanenko, Viatcheslav; Merced, Francisco G.; Ayala, Angel M.; Correa, Wildeliz; De Jesus, Melvin
Organic Letters, 2007 , vol. 9, # 9 p. 1793 - 1795
反应条件
hydrogen; Pd-BaSO4 in toluene T=70°C; P=75.0075 Torr;
参考文献
Parvulescu, Andrei N.; Jacobs, Pierre A.; De Vos, Dirk E.
Chemistry - A European Journal, 2007 , vol. 13, # 7 p. 2034 - 2043
反应条件
1: With sodium carbonate in toluene T=90°C; 72 h; 2: With hydrogen; palladium on activated charcoal in ethanol T=20°C; P=760.051 Torr; 0.5 h; Further stages. Title compound not separated from byproducts.;
参考文献
Hoben, Christine E.; Kanupp, Lisa; Baeckvall, Jan-E.
Tetrahedron Letters, 2008 , vol. 49, # 6 p. 977 - 979
反应条件
Candida antartica lipase B T=20°C; Enzymatic reaction; optical yield given as percent ee;
参考文献
Paeivioe, Mari; Perkioe, Paeivi; Kanerva, Liisa T.
Tetrahedron Asymmetry, 2012 , vol. 23, # 3-4 p. 230 - 236
反应条件
ammonium formate; palladium on activated charcoal in methanol 0.5 h; Heating; Yields of byproduct given;
参考文献
Bringmann, G.; Geisler, J.-P.
Journal of Fluorine Chemistry, 1990 , vol. 49, # 1 p. 67 - 73
反应条件
bis-[(trifluoroacetoxy)iodo]benzene in water; acetonitrile Ambient temperature;
参考文献
Loudon, G. Marc; Radhakrishna, A. S.; Almond, Merrick R.; Blodgett, James K.; Boutin, Raymond H.
Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4272 - 4276
反应条件
dimethylsulfide borane complex; enantiopure spiroborate ester in tetrahydrofuran T=25°C; 36 h; Title compound not separated from byproducts.;
参考文献
Huang, Xiaogen; Ortiz-Marciales, Margarita; Huang, Kun; Stepanenko, Viatcheslav; Merced, Francisco G.; Ayala, Angel M.; Correa, Wildeliz; De Jesus, Melvin
Organic Letters, 2007 , vol. 9, # 9 p. 1793 - 1795
反应条件
Pseudomonas cepacia lipase PSL-C in various solvent(s) T=30°C; 32 h; Enzymatic reaction;
参考文献
De Miranda, Amanda S.; Miranda, Leandro S. M.; De Souza, Rodrigo O. M. A.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 20 p. 3332 - 3336
反应条件
1: With periodic acid; methylamine in methanol; water T=20°C; 3 h; 2: With hydrogenchloride in methanol 0.5 h; Further stages.;
参考文献
Lamblin, Marc; Couture, Axel; Deniau, Eric; Grandclaudon, Pierre
Tetrahedron Asymmetry, 2008 , vol. 19, # 1 p. 111 - 123