alpha-溴-4-甲氧基苯乙酮合成路线 （共 261 条）
参考文献
Nitta, Aiko; Fujii, Hideaki; Sakami, Satoshi; Satoh, Mikiya; Nakaki, Junko; Satoh, Shiho; Kumagai, Hiroki; Kawai, Hideki
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 23 p. 7036 - 7040
反应条件
Rasta resin-PPh3-NBniPr2 in chloroform T=60°C; Wittig reaction; Molecular sieve;
参考文献
Lu, Jinni; Toy, Patrick H.
Chemistry - An Asian Journal, 2011 , vol. 6, # 9 p. 2251 - 2254
反应条件
1: 80.4 percent / KOH / ethanol; H2O; ethyl acetate / Ambient temperature 2: 69 percent / PPA / 1 h / 85 - 90 °C 3: AlCl3 / CH2Cl2 / 1.5 h / 27 - 29 °C 4: 77.5 percent / AlCl3, EtSH / CH2Cl2 / 0.5 h / Ambient temperature View Scheme
参考文献
Jones, Charles D.; Jevnikar, Mary G.; Pike, Andrew J.; Peters, Mary K.; Black, Larry J.; at al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 1057 - 1066
反应条件
acetic acid in ethanol; water 2.5 h; Heating;
参考文献
Kaila, Neelu; Janz, Kristin; DeBernardo, Silvano; Bedard, Patricia W.; Camphausen, Raymond T.; Tam, Steve; Tsao, Desiree H.H.; Keith Jr., James C.; Nickerson-Nutter, Cheryl; Shilling, Adam; Young-Sciame, Ruth; Wang, Qin
Journal of Medicinal Chemistry, 2007 , vol. 50, # 1 p. 21 - 39
反应条件
potassium acetate in methanol
参考文献
Givaudan Roure ( International ) SA
Patent: US6258854 B1, 2001 ;
参考文献
Hayashi
Acta Phytochimica, 1933 , vol. 7, p. 117,138
Acta Phytochimica, 1934 , vol. 8, p. 65,93
反应条件
triethylamine in acetone
参考文献
Sakuragi; Tokumaru; Itoh; Terakawa; Kikuchi; Caldwell; Hsu
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 4 p. 1049 - 1057
反应条件
in ethanol; water 2.5 h; Reflux;
参考文献
Nguyen, John D.; Matsuura, Bryan S.; Stephenson, Corey R. J.
Journal of the American Chemical Society, 2014 , vol. 136, # 4 p. 1218 - 1221
反应条件
sodium ethanolate in ethanol
参考文献
Kaspersen, Svein Jacob; Hoff, Bard Helge; Sundby, Eirik; Charnock, Colin
Bioorganic Chemistry, 2012 , vol. 44, p. 35 - 41,7
反应条件
1: NaBH4; 2-(3-NO2-Ph)-1,3,2-dioxaborolane-(4R,5R)-dicarboxylic acid / tetrahydrofuran / 25 °C 2: aq. NaOH / tetrahydrofuran / 25 °C View Scheme
参考文献
Cordes, David B.; Kwong, Tracey J.; Morgan, Kellie A.; Singaram, Bakthan
Tetrahedron Letters, 2006 , vol. 47, # 3 p. 349 - 351
