1-(4-溴苯基)-2-硫代脲合成路线 （共 15 条）
反应条件
sodium hydroxide; water in ethanol 1 h; Heating / reflux;
参考文献
An, Haoyun; Xi, Biao; Abassi, Yama; Wang, Xiaobo; Xu, Xiao
Patent: US2009/48271 A1, 2009 ;
Location in patent: Page/Page column 18 ;
参考文献
Fujifilm RI Pharma Co., Ltd.; Daiichi Sankyo Company, Limited
Patent: EP1956013 A1, 2008 ;
Location in patent: Page/Page column 25 ;
反应条件
hydrogenchloride in water 0.5 h;
参考文献
Gupta, Mahesh Kumar; Pandeya, Suerendra N.; Zaiad, Golal M.; Gangwar
Journal of the Indian Chemical Society, 2010 , vol. 87, # 11 p. 1421 - 1424
反应条件
ammonium hydroxide in ethanol 1 h; Heating;
参考文献
Hanefeld
Archiv der Pharmazie, 1980 , vol. 313, # 12 p. 1006 - 1012
反应条件
1: calcium carbonate / water; dichloromethane / 19.5 h / 0 - 20 °C / |Inert atmosphere 2: ammonia / tetrahydrofuran / 25 °C View Scheme
参考文献
Holla, B. Shivarama; Malini; Rao, B. Sooryanarayana; Sarojini; Kumari, N. Suchetha
European Journal of Medicinal Chemistry, 2003 , vol. 38, # 3 p. 313 - 318
反应条件
in tetrahydrofuran Addition; Heating;
参考文献
Herr; Kuhler; Meckler; Opalka
Synthesis, 2000 , # 11 p. 1569 - 1574
反应条件
1: para-bromoaniline hydrochloride With hydrogenchloride in water 0.5 h; Reflux; 2: ammonium thiocyanate in water T=20°C; 4 h; Reflux;
参考文献
Sharma, Pratibha; Kumar, Ashok; Kumari, Prerna; Singh, Jitendra; Kaushik
Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1136 - 1148
反应条件
in methanol T=25°C; 4-bromophenolate buffer; Rate constant;
参考文献
Kavalek, Jaromir; El Bahaie, Said; Sterba, Vojeslav
Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 9 p. 2103 - 2110
反应条件
water; potassium carbonate in PEG 400 T=80°C; 2 h;
参考文献
Yella, Ramesh; Singh, Raman Kumar; Majji, Ganesh; Patel, Bhisma K.
Journal of Sulfur Chemistry, 2012 , vol. 33, # 1 p. 43 - 47
反应条件
1: bromine / chloroform / 4 h / 5 °C 2: potassium hydroxide / water / |Reflux View Scheme
参考文献
Kumar, Mahendra; Sharma, Kailash; Fogla, Ankur Kumar; Sharma, Kanika; Rathore, Madhu
Research on Chemical Intermediates, 2013 , vol. 39, # 6 p. 2555 - 2564
