4,4-二甲基恶唑-2-酮合成路线 （共 23 条）
参考文献
Jones, Simon; Smanmoo, Chaiwat
Tetrahedron Letters, 2004 , vol. 45, # 8 p. 1585 - 1588
反应条件
nitromethane 0.0833333 h; Microwave irradiation;
参考文献
Bratulescu, George
Asian Journal of Chemistry, 2011 , vol. 23, # 2 p. 929 - 930
反应条件
in diethyl ether 0.166667 h; Ambient temperature;
参考文献
Chadwick, Derek J.; Ngochindo, Raphael I.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 3 p. 481 - 486
反应条件
1: methanol; potassium carbonate / 1,2-dichloro-ethane / Inert atmosphere 2: [Cu(MeCN)]4PF6; C20H20N4O4; iodosylbenzene / acetonitrile / 45 °C / Molecular sieve; Inert atmosphere View Scheme
参考文献
Barman, Dipti N.; Nicholas, Kenneth M.
European Journal of Organic Chemistry, 2011 , # 5 p. 908 - 911
参考文献
Katchalski; Ishai
Journal of Organic Chemistry, 1950 , vol. 15, p. 1067,1071
反应条件
potassium sec-butyl carbonate; xylene; benzene
参考文献
Mallinckrodt Chem. Works
Patent: US2399118 , 1942 ;
反应条件
in dichloromethane 1.) -78 deg C, 15 min, 2.) 25 deg C, 12 h; Yield given. Yields of byproduct given;
参考文献
Lorincz, Tibor; Erden, Ihsan; Naeder, Reinhard; Meijere, Armin de
Synthetic Communications, 1986 , vol. 16, # 2 p. 123 - 130
反应条件
Erhitzen des Reaktionsprodukts unter vermindertem Druck;
参考文献
Katchalski; Ishai
Journal of Organic Chemistry, 1950 , vol. 15, p. 1067,1071
反应条件
methylmagnesium bromide 1.) THF, ether, 0 deg C, 10 min, 2.) THF, ether, a.) -78 deg C, 10 min, b.) 0 deg C, 20 min; Yield given. Multistep reaction;
参考文献
Chapuis, C.; Jurczak, J.
Polish Journal of Chemistry, 1994 , vol. 68, # 1 p. 99 - 108
参考文献
Sumitomo Pharmaceuticals Company, Limited
Patent: US5231179 A1, 1993 ;
