5,6-亚甲基二氧基吲哚合成路线 （共 23 条）
反应条件
1: 1.) aq. HCl, formic acid, NaNO2, 2.) NaN3; / 1.) acetic acid, 70 min, -5 deg C, 2.) 20 min; 2: 67 percent / various solvent(s) / 0.07 h / Heating View Scheme
参考文献
Lutz; McNamara; Olinger; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1183 - 1188
反应条件
1: SnCl2, conc. HCl 2: 1.) aq. HCl, formic acid, NaNO2, 2.) NaN3; / 1.) acetic acid, 70 min, -5 deg C, 2.) 20 min; 3: 67 percent / various solvent(s) / 0.07 h / Heating View Scheme
参考文献
Lutz; McNamara; Olinger; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1183 - 1188
参考文献
Burton; Duffield
Journal of the Chemical Society, 1949 , p. 78
反应条件
1: KOH / ethanol / 14 h / Heating 2: H2 / PtO2 / acetic acid; ethanol / 20 h View Scheme
参考文献
Balle, Thomas; Perregaard, Jens; Larsen, Anna K.; Ramirez, Martha Teresa; Soby, Karina Krojer; Liljefors, Tommy; Andersen, Kim
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 6 p. 1065 - 1078
反应条件
1: diethyl ether / 0.5 h / 0 °C
2: 41 percent / tetrahydrofuran; diethyl ether / 0 °C / pH > 9
3: 25 percent / LiAlH4 / tetrahydrofuran / Heating
View Scheme
参考文献
Grotjahn
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 4 p. 1031 - 1036
反应条件
1: diethyl ether / 0.5 h / 0 °C
2: 58 percent / tetrahydrofuran; diethyl ether / 0 °C / pH > 9
View Scheme
参考文献
Grotjahn
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 4 p. 1031 - 1036
反应条件
1: diethyl ether / 0.5 h / 0 °C
2: 41 percent / tetrahydrofuran; diethyl ether / 0 °C / pH > 9
3: 58 percent / LiAlH4 / tetrahydrofuran / Heating
View Scheme
参考文献
Grotjahn
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 4 p. 1031 - 1036
反应条件
1: diethyl ether / 0.5 h / 0 °C
2: 44 percent / tetrahydrofuran; diethyl ether / 0 °C / pH > 9
View Scheme
参考文献
Grotjahn
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 4 p. 1031 - 1036
反应条件
1: diethyl ether / 0.5 h / 0 °C
2: 46 percent / tetrahydrofuran; diethyl ether / 0 °C / pH > 9
View Scheme
参考文献
Grotjahn
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 4 p. 1031 - 1036
反应条件
1: diethyl ether / 0.5 h / 0 °C
2: 58 percent / tetrahydrofuran; diethyl ether / 0 °C / pH > 9
3: 68 percent / LiAlH4 / tetrahydrofuran / Heating
View Scheme
参考文献
Grotjahn
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 4 p. 1031 - 1036
