4-(2-哌啶-1-乙氧基)苯甲醛合成路线 （共 8 条）
反应条件
potassium carbonate; sodium iodide in acetone 18 h; Reflux;
参考文献
Huang, Jing; Li, Guorui; Wu, Zhiguo; Song, Zhibin; Zhou, Yangyang; Shuai, Liang; Weng, Xiaocheng; Zhou, Xiang; Yang, Guangfu
Chemical Communications, 2009 , # 8 p. 902 - 904
反应条件
in methanol; water T=20°C; 60 h;
参考文献
Nagarapu, Lingaiah; Aneesa; Satyender, Apuri; Chandana; Bantu, Rajaskaker
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 2 p. 195 - 200
反应条件
manganese(IV) oxide in chloroform T=20°C;
参考文献
Eisai Co., Ltd.
Patent: EP1577288 A1, 2005 ;
Location in patent: Page/Page column 87 ;
EP 1577288 A1
反应条件
potassium carbonate in N,N-dimethyl-formamide T=60°C; 16 h;
参考文献
Endorecherche Inc.
Patent: EP1167364 A1, 2002 ;
Location in patent: Example 1 ;
反应条件
dihydrogen peroxide; triphenylphosphine in tetrahydrofuran; methanol; dichloromethane
参考文献
ELI LILLY AND COMPANY
Patent: EP873992 A1, 1998 ;
EP 0873992 A1
反应条件
Ki in methanol; chloroform; N,N-dimethyl-formamide
参考文献
American Home Products Corporation
Patent: US6005102 A1, 1999 ;
US 6005102 A
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in dichloromethane T=20°C; Mitsunobu reaction;
参考文献
Wu, Ying; Tai, Hsin-Hsiung; Cho, Hoon
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 4 p. 1428 - 1433
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 80 °C 2: potassium carbonate / N,N-dimethyl-formamide / 6 h / 80 °C View Scheme
参考文献
Manohar, Sunny; Khan, Shabana I.; Kandi, Shamseer Kulangara; Raj, Kranthi; Sun, Guojing; Yang, Xiaochuan; Calderon Molina, Angie D.; Ni, Nanting; Wang, Binghe; Rawat, Diwan S.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 112 - 116
