1-(烯丙基)吡咯烷-2-酮合成路线 （共 19 条）
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; caesium carbonate; tris(p-fluoro phenyl)phosphine in dichloromethane
T=20°C; Tsuji-Trost allylation;
参考文献
Aoyagi, Kouichi; Nakamura, Hiroyuki; Yamamoto, Yoshinori
Journal of Organic Chemistry, 2002 , vol. 67, # 17 p. 5977 - 5980
参考文献
Kulig, Katarzyna; Holzgrabe, Ulrike; Malawska, Barbara
Tetrahedron Asymmetry, 2001 , vol. 12, # 18 p. 2533 - 2536
反应条件
1: 1.) NaBH4, 2.) TsOH
2: 89 percent / n-Bu3SnH, AIBN
View Scheme
参考文献
Burnett, Duane A.; Choi, Joong-Kwon; Hart, David J.; Tsai, Yeun-Min
Journal of the American Chemical Society, 1984 , vol. 106, # 26 p. 8201 - 8209
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride
参考文献
Crich, David; Eustace, K. Angeline; Ritchie, Timothy J.
Heterocycles, 1989 , vol. 28, # 1 p. 67 - 70
反应条件
p-nitrobenzenesulfonyl peroxide
1.) -78 deg C, dichloromethane, 2.) 25 deg C; Yield given. Multistep reaction;
参考文献
Hoffman, Robert V.; Salvador, James M.
Tetrahedron Letters, 1989 , vol. 30, # 32 p. 4207 - 4210
反应条件
1: 69 percent / mixed anhydride
2: 73 percent / tri-n-butyltin hydride, azobis(isobutyronitrile)
View Scheme
参考文献
Crich, David; Eustace, K. Angeline; Ritchie, Timothy J.
Heterocycles, 1989 , vol. 28, # 1 p. 67 - 70
反应条件
1: 72 percent / saponification
2: 69 percent / mixed anhydride
3: 73 percent / tri-n-butyltin hydride, azobis(isobutyronitrile)
View Scheme
参考文献
Crich, David; Eustace, K. Angeline; Ritchie, Timothy J.
Heterocycles, 1989 , vol. 28, # 1 p. 67 - 70
反应条件
water; oxygen; copper dichloride; palladium dichloride in tetrahydrofuran
T=50°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Hosokawa; Aoki; Takano; Nakahira; Yoshida; Murahashi
Journal of the Chemical Society - Series Chemical Communications, 1991 , # 21 p. 1559 - 1560
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; dichloro bis(acetonitrile) palladium(II); oxygen; copper(l) chloride in 1,2-dichloro-ethane
Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Hosokawa; Aoki; Takano; Nakahira; Yoshida; Murahashi
Journal of the Chemical Society - Series Chemical Communications, 1991 , # 21 p. 1559 - 1560
