3,5-双(1-甲基乙基)苯酚合成路线 （共 14 条）
反应条件
aluminum tri-bromide T=169.9°C; 33 h; other catalyst (AlCl3), temperature, time, ΔHr, ΔSr; Thermodynamic dataEquilibrium constantProduct distribution;
参考文献
Nesterova, T. N.; Pilyshchikov, V. A.; Rozhnov, A. M.
J. Appl. Chem. USSR (Engl. Transl.), 1983 , vol. 56, # 6 p. 1338 - 1342,1257 - 1261
反应条件
1: 1.) oxalyl chloride, DMF, 2.) Et3N, DMAP / 1.) CH2Cl2, 0 deg, 1 h -> r. t., 3 h, 2.) CHCl2, r. t., 3 h 2: 72 percent / NaOAc / bis(triphenylphosphane)palladium dichloride / N,N-dimethyl-acetamide / 130 °C View Scheme
参考文献
Bringmann, Gerhard; Hartung, Thomas; Goebel, Lothar; Schupp, Olaf; Ewers, Christian L. J.; et al.
Liebigs Annalen der Chemie, 1992 , # 3 p. 225 - 232
反应条件
1: With 2-hydroxy-1,3-isoindolinedione; 2,2'-azo-bisisobutyronitrile; oxygen in acetonitrile
T=75°C; P=760 Torr; 2 h;
2: With sulfuric acid in acetonitrile
T=20°C; 2 h; Title compound not separated from byproducts;
参考文献
Aoki, Yasuhiro; Hirai, Naruhisa; Sakaguchi, Satoshi; Ishii, Yasutaka
Tetrahedron, 2005 , vol. 61, # 46 p. 10995 - 10999
反应条件
aluminum oxide; nickel sulphate in various solvent(s)
T=280°C; fixed, quartz powder bed tubular reactor; gaseous phase in N2 flow; conversion and selectivity studied; Product distribution;
参考文献
Yao, Benjamin; Bassus, Jacques; Lamartine, Roger; Gauvrit, Jean-Yves; Lanteri, Pierre; Longeray, Remi
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 5 p. 477 - 480
反应条件
tetraethylammonium bromide in water; N,N-dimethyl-formamide
electrolysis;
参考文献
Akbulut, Ural; Toppare, Levent; Utley, James H. P.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 391 - 394
反应条件
1: air; aqueous Na2CO3
2: HClO4; acetic acid
View Scheme
参考文献
Seidel et al.
Journal fuer Praktische Chemie (Leipzig), 1956 , vol. <4> 3, p. 278,297
反应条件
(i) Mg, Et2O, (ii) (oxidation); Multistep reaction;
参考文献
Le Noble,W.J. et al.
Journal of Organic Chemistry, 1971 , vol. 36, p. 193 - 196
反应条件
(i) NaNO2, aq. H2SO4, (ii) (heating); Multistep reaction;
参考文献
Kovacic,P. et al.
Journal of Organic Chemistry, 1967 , vol. 32, p. 585 - 588
反应条件
2: (i) Mg, Et2O, (ii) (oxidation)
View Scheme
参考文献
Le Noble,W.J. et al.
Journal of Organic Chemistry, 1971 , vol. 36, p. 193 - 196
反应条件
aluminium trichloride
T=169.9°C; 10 h; other catalyst (AlBr3), temperature, time, ΔHr, ΔSr; Thermodynamic dataEquilibrium constantProduct distribution;
参考文献
Nesterova, T. N.; Pilyshchikov, V. A.; Rozhnov, A. M.
J. Appl. Chem. USSR (Engl. Transl.), 1983 , vol. 56, # 6 p. 1338 - 1342,1257 - 1261
