water in dichloromethane (N2); addn. of HBBr2(SMe2) at 0°C; filtration after 12 h into mixture of ice and ether (1:1); stirring for 30 min at room temperature; washing of organic phase with satd. NaCl-soln.; drying (MgSO4); removal of solvent in vac.; washing with hexane;
参考文献
Jego, J. M.; Carboni, B.; Vaultier, M.
Bulletin de la Societe Chimique de France, 1992 , vol. 129, p. 554 - 565
2,2'-azo-bisisobutyronitrile in toluene byproducts: CH2CH(CH2)3CH3, C5H9CH3, C6H12; 6-bromo-1-hexene and azobisisobutyronitrile (catalyst) were added to soln. of Sn hydride in toluene under Ar; mixt. was refluxed for 3 h; distd.; chromd.;
参考文献
Journal of Organometallic Chemistry, , vol. 691, # 6 p. 1085 - 1091
1: D-(-)-sodium lactate With potassium tert-butylate in dimethyl sulfoxide T=15 - 20°C; 1.5 h; Inert atmosphere; 2: 5-hexenyl bromide in dimethyl sulfoxide T=20°C; 21 h; 3: With hydrogenchloride in water T=0°C; pH=1 - 2;
参考文献
PHENOMIX CORPORATION; BETANCORT, Juan Manuel; HEPPERLE, Michael E.; CAMPBELL, David Alan; WINN, David T.
Patent: WO2010/33466 A1, 2010 ;
Location in patent: Page/Page column 66 ;
WO 2010/033466 A1
