1: 1-bromomethyl-4-methoxy-benzene With diethylphosphinoethane T=0 - 20°C; 0.5 h; Inert atmosphere; 2: With lithium hydroxide hydrate in water T=20°C; 0.0333333 h; 3: 3,4,5-trimethoxy-benzaldehyde in water T=70°C; Wittig reaction; 3 h;
参考文献
McNulty, James; Das, Priyabrata
European Journal of Organic Chemistry, 2009 , # 24 p. 4031 - 4035
1: toluene / 6 h / Heating 2: 0.4 g / n-butyllithium / hexane; tetrahydrofuran / 16 h / -78 °C View Scheme
参考文献
Heynekamp, Justin J.; Weber, Waylon M.; Hunsaker, Lucy A.; Gonzales, Amanda M.; Orlando, Robert A.; Deck, Lorraine M.; Vander Jagt, David L.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 24 p. 7182 - 7189
