1,3-二甲基-5-吡唑酮合成路线 （共 36 条）
反应条件
1: trichlorophosphate 2: potassium permanganate 3: thionyl chloride View Scheme
参考文献
Wu, Jian; Shi, Qing; Chen, Zhuo; He, Ming; Jin, Linhong; Hu, Deyu
Molecules, 2012 , vol. 17, # 5 p. 5139 - 5150
反应条件
trichlorophosphate T=130°C; Vilsmeier-Haack reaction; 1 h;
参考文献
El-Baih, Fatma E.M.; Al-Hazimi, Hassan M.
Asian Journal of Chemistry, 2011 , vol. 23, # 3 p. 1309 - 1313
反应条件
1: 72 percent / triethylamine / benzene 2: 29 percent / phosphoryl chloride / 2 h / Heating 3: 92 percent / NaOH / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 72 percent / triethylamine / benzene 2: 29 percent / phosphoryl chloride / 2 h / Heating 3: 92 percent / NaOH / ethanol; H2O / 2 h / Heating 4: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 72 percent / triethylamine / benzene 2: 29 percent / phosphoryl chloride / 2 h / Heating 3: 92 percent / NaOH / ethanol; H2O / 2 h / Heating 4: 70 percent / conc. H2SO4 / 48 h / Heating 5: 93 percent / anhydrous sodium acetate, H2 / 5percent Pd/C / ethanol / 1520 Torr / Ambient temperature View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 72 percent / triethylamine / benzene 2: 29 percent / phosphoryl chloride / 2 h / Heating 3: 92 percent / NaOH / ethanol; H2O / 2 h / Heating 4: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature 5: Heating View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: POCl3 / 120 °C 2: KOH / dimethylformamide / 120 °C View Scheme
参考文献
Park, Hyun-Ja; Lee, Kyung; Park, Su-Jin; Ahn, Bangle; Lee, Jong-Cheol; Cho, HeeYeong; Lee, Kee-In
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 13 p. 3307 - 3312
反应条件
1: POCl3 / 120 °C 2: KOH / dimethylformamide / 120 °C 3: NH2OH; NaOH / methanol / 60 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 13 p. 3307 - 3312
反应条件
1: POCl3 / Heating View Scheme
参考文献
Li, Yan; Zhang, Hong-Quan; Liu, Jie; Yang, Xiang-Ping; Liu, Zhao-Jie
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 10 p. 3636 - 3640
反应条件
1: 72 percent / triethylamine / benzene 2: 29 percent / phosphoryl chloride / 2 h / Heating 3: 92 percent / NaOH / ethanol; H2O / 2 h / Heating 4: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature 5: thionyl chloride / Heating View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
