5,6,7,8-四氢喹噁啉-2-醇合成路线 （共 6 条）
反应条件
sodium hydroxide in methanol; water
参考文献
Neurogen Corporation
Patent: US5306819 A1, 1994 ;
US 5306819 A
反应条件
in benzene 1.5 h; Irradiation;
参考文献
Ohkanda, Junko; Kumasaka, Toshihiko; Takasu, Aki; Hasegawa, Tadashi; Katoh, Akira
Heterocycles, 1996 , vol. 43, # 4 p. 883 - 889
反应条件
1: 41 percent / ethanol; H2O 2: 58 percent / NEt3 / dimethylsulfoxide / 24 h / Ambient temperature 3: 64 percent / benzene / 1.5 h / Irradiation View Scheme
参考文献
Ohkanda, Junko; Kumasaka, Toshihiko; Takasu, Aki; Hasegawa, Tadashi; Katoh, Akira
Heterocycles, 1996 , vol. 43, # 4 p. 883 - 889
反应条件
trichlorophosphate 3 h; Heating / reflux;
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: EP1196410 B1, 2004 ;
Location in patent: Page 34 ;
参考文献
Neurogen Corporation
Patent: US5306819 A1, 1994 ;
US 5306819 A
反应条件
sodium methylate in methanol
1 h; Heating;
参考文献
Nishio, Takehiko; Kondo, Masaji; Omote, Yoshimori
Helvetica Chimica Acta, 1991 , vol. 74, # 1 p. 225 - 231
