甲基3-(3’,4’-二甲氧基苯基)丙酸酯合成路线 (共 17 条)
反应条件
diethyl ether; aluminium amalgam
参考文献
Lewis; Ramage; Robinson
Journal of the Chemical Society, 1935 , p. 1412
参考文献
Lewis; Ramage; Robinson
Journal of the Chemical Society, 1935 , p. 1412
反应条件
1: benzene; hydrazine hydrate 2: aqueous hydrochloric acid; aqueous sodium nitrite solution 3: benzene View Scheme
参考文献
Mohunta; Ray
Journal of the Chemical Society, 1934 , p. 1263
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1932 , vol. 270, p. 353,359
反应条件
1: benzene; hydrazine hydrate
2: aqueous hydrochloric acid; aqueous sodium nitrite solution
3: benzene
4: toluene
View Scheme
参考文献
Mohunta; Ray
Journal of the Chemical Society, 1934 , p. 1263
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Chemex Pharmaceuticals, Inc.
Patent: US4954659 A1, 1990 ;
反应条件
lithium borohydride in diethyl ether; toluene
0.25 h; Heating;
参考文献
Kita, Yasuyuki; Egi, Masahiro; Ohtsubo, Makoto; Saiki, Toyokazu; Okajima, Akiko; Takada, Takeshi; Tohma, Hirofumi
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 2 p. 241 - 245