beta-D-5-脱氧呋喃木糖三乙酸酯合成路线 （共 28 条）
反应条件
2,6-di-tert-butyl-4-methylpyridinium triflate in acetonitrile T=140°C;
参考文献
Shen, Bo; Jamison, Timothy F.
Organic Letters, 2012 , vol. 14, # 13 p. 3348 - 3351
反应条件
2,6-di-tert-butyl-4-methylpyridinium triflate in acetonitrile T=130°C;
参考文献
Shen, Bo; Jamison, Timothy F.
Organic Letters, 2012 , vol. 14, # 13 p. 3348 - 3351
反应条件
1.1: HMDS / toluene / 3 h / 100 °C 1.2: 76 percent / SnCl4 / CH2Cl2 / 2 h / 20 °C 2.1: 1311 g / pyridine / CH2Cl2 / -20 - 20 °C View Scheme
参考文献
Shimma, Nobuo; Umeda, Isao; Arasaki, Motohiro; Murasaki, Chikako; Masubuchi, Kazunao; Kohchi, Yasunori; Miwa, Masanori; Ura, Masako; Sawada, Noriaki; Tahara, Hitoshi; Kuruma, Isamu; Horii, Ikuo; Ishitsuka, Hideo
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1697 - 1706
反应条件
1.1: HMDS / toluene / 3 h / 100 °C 1.2: 76 percent / SnCl4 / CH2Cl2 / 2 h / 20 °C 2.1: pyridine / CH2Cl2 / -20 - 20 °C 3.1: NaOH / methanol; H2O / -20 - -5 °C View Scheme
参考文献
Shimma, Nobuo; Umeda, Isao; Arasaki, Motohiro; Murasaki, Chikako; Masubuchi, Kazunao; Kohchi, Yasunori; Miwa, Masanori; Ura, Masako; Sawada, Noriaki; Tahara, Hitoshi; Kuruma, Isamu; Horii, Ikuo; Ishitsuka, Hideo
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1697 - 1706
反应条件
1: 2,6-di-tert-butyl-4-methylpyridinium triflate / acetonitrile / 80 °C 2: water; sodium hydroxide / methanol / 0.03 h / 20 °C View Scheme
参考文献
Shen, Bo; Jamison, Timothy F.
Organic Letters, 2012 , vol. 14, # 13 p. 3348 - 3351
反应条件
1: 2,6-di-tert-butyl-4-methylpyridinium triflate / acetonitrile / 130 °C 2: water; sodium hydroxide / methanol / 0.03 h / 20 °C View Scheme
参考文献
Shen, Bo; Jamison, Timothy F.
Organic Letters, 2012 , vol. 14, # 13 p. 3348 - 3351
反应条件
1.1: HMDS / toluene / 3 h / 100 °C 1.2: 76 percent / SnCl4 / CH2Cl2 / 2 h / 20 °C 2.1: 1311 g / pyridine / CH2Cl2 / -20 - 20 °C 3.1: 170 g / NaOH / methanol; H2O / -20 - -5 °C View Scheme
参考文献
Shimma, Nobuo; Umeda, Isao; Arasaki, Motohiro; Murasaki, Chikako; Masubuchi, Kazunao; Kohchi, Yasunori; Miwa, Masanori; Ura, Masako; Sawada, Noriaki; Tahara, Hitoshi; Kuruma, Isamu; Horii, Ikuo; Ishitsuka, Hideo
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1697 - 1706
反应条件
1: 5-fluoro-cytosine With trifluorormethanesulfonic acid; 1,1,1,3,3,3-hexamethyl-disilazane in acetonitrile 2 h; Reflux; 2: 1,2,3-tri-O-acetyl-5-deoxy-β-D-ribofuranose With trifluorormethanesulfonic acid T=20 - 55°C;
参考文献
ScinoPharm Taiwan Ltd.
Patent: US2011/21769 A1, 2011 ;
Location in patent: Page/Page column 3; 5 ;
