反应条件
1: ethanol / 18 h / 80 °C / Inert atmosphere 2: triethylamine / diethyl ether / 0.5 h / 0 °C / Inert atmosphere 3: diethyl ether; water / 18 h / 10 - 20 °C / Inert atmosphere; Cooling with ice 4: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C / Inert atmosphere 5: hydrogenchloride / diethyl ether; ethyl acetate / Inert atmosphere View Scheme
参考文献
Smith, Victoria C.; Cleghorn, Laura A. T.; Woodland, Andrew; Spinks, Daniel; Hallyburton, Irene; Collie, Iain T.; YiMok; Norval, Suzanne; Brenk, Ruth; Fairlamb, Alan H.; Frearson, Julie A.; Read, Kevin D.; Gilbert, Ian H.; Wyatt, Paul G.
ChemMedChem, 2011 , vol. 6, # 10 p. 1832 - 1840