5,6,7,8-四氢-3-甲基喹啉合成路线 （共 52 条）
反应条件
sodium hydroxide; hydrazine hydrate in diethylene glycol
参考文献
John Wyeth and Brother Limited
Patent: US4092317 A1, 1978 ;
反应条件
tetrahydropyridine hydrochloride in toluene T=200°C; 2 h; autoclave;
参考文献
Vijn; Arts; Green; Castelijns
Synthesis, 1994 , # 6 p. 573 - 578
反应条件
trichlorophosphate in 1,2-dichloro-ethane cyclocondensation; 4 h; Heating;
参考文献
Boruah, Romesh C.; Ahmed, Shahadat; Sharma, Utpal; Sandhu, Jagir S.
Journal of Organic Chemistry, 2000 , vol. 65, # 3 p. 922 - 925
反应条件
nickel; decalin T=190°C; P=15200 Torr; Hydrogenation;
参考文献
v. Braun; Gmelin; Schultheiss
Chemische Berichte, 1923 , vol. 56, p. 1343
反应条件
1: 70 percent / dicarbonyl(cyclopentadienyl)cobalt / m-xylene / Heating; Irradiation 2: Me4N(1+)*F(1-) / methanol / 0.5 h / 50 °C View Scheme
参考文献
Brien, David J.; Naiman, Alaric; Vollhardt, K. Peter C.
Journal of the Chemical Society, Chemical Communications, 1982 , # 2 p. 133 - 134
反应条件
1: 69 percent / POCl3 / CH2Cl2 / 3 h / 0 - 15 °C 2: 52 percent / POCl3 / 1,2-dichloro-ethane / 4 h / Heating View Scheme
参考文献
Boruah, Romesh C.; Ahmed, Shahadat; Sharma, Utpal; Sandhu, Jagir S.
Journal of Organic Chemistry, 2000 , vol. 65, # 3 p. 922 - 925
反应条件
1: 74 percent / p-TsOH / toluene / 24 h / Heating 2: 69 percent / POCl3 / CH2Cl2 / 3 h / 0 - 15 °C 3: 52 percent / POCl3 / 1,2-dichloro-ethane / 4 h / Heating View Scheme
参考文献
Koyama, Junko; Sugita, Teruyo; Suzuta, Yukio; Irie, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2601 - 2606
反应条件
in toluene T=200°C; 2 h; autoclave;
参考文献
Vijn; Arts; Green; Castelijns
Synthesis, 1994 , # 6 p. 573 - 578
参考文献
Koyama, Junko; Sugita, Teruyo; Suzuta, Yukio; Irie, Hiroshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2601 - 2606
反应条件
1: 120 - 130 °C 2: nickel; tetralin / 190 °C / 15200 Torr / Hydrogenation View Scheme
参考文献
v. Braun; Gmelin; Schultheiss
Chemische Berichte, 1923 , vol. 56, p. 1343
