四氢-(2H)-1,4-硫氮杂革-5-酮合成路线 （共 14 条）
反应条件
1: With hydrogenchloride; sodium azide in water T=0 - 20°C; 4 h; 2: With sodium carbonate in water
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1486490 A1, 2004 ;
Location in patent: Page 46 ;
反应条件
n-butyllithium; triethylamine in 1,4-dioxane; hexane
参考文献
Merck and Co., Inc.
Patent: US6043358 A1, 2000 ;
反应条件
sodium carbonate in hydrogenchloride; water
参考文献
Pharmacia and Upjohn Company
Patent: US6248739 B1, 2001 ;
参考文献
Grob,C.A.; Ide,J.
Helvetica Chimica Acta, 1974 , vol. 57, p. 2562 - 2571
反应条件
triethylamine in 1,4-dioxane T=20°C; Beckmann rearrangement;
参考文献
Shankaran; Donnelly, Karla L.; Shah, Shrenik K.; Caldwell, Charles G.; Chen, Ping; Hagmann, William K.; MacCoss, Malcolm; Humes, John L.; Pacholok, Stephen G.; Kelly, Theresa M.; Grant, Stephan K.; Wong, Kenny K.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 23 p. 5907 - 5911
反应条件
in methanol T=20°C; 2 h;
参考文献
Yang, Xiaofeng; Guo, Yixing; Strongin, Robert M.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 14 p. 2739 - 2741,3
反应条件
sodium methylate in methanol
参考文献
Jakob,F.; Schlack,P.
Chemische Berichte, 1963 , vol. 96, p. 88 - 92
反应条件
N-benzyl-trimethylammonium hydroxide in methanol
参考文献
Jakob,F.; Schlack,P.
Chemische Berichte, 1963 , vol. 96, p. 88 - 92
反应条件
in ethanol pH=7.4; aq. phosphate bufferIrradiation;
参考文献
Yang, Xiaofeng; Guo, Yixing; Strongin, Robert M.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 45 p. 10690 - 10693
参考文献
Arya,V.P. et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1977 , vol. 15, p. 720 - 726
