5-(2-硝基苯基)-2-糠酸合成路线 （共 6 条）
反应条件
1: 2-nitro-aniline With hydrogenchloride; water; sodium nitrite T=0 - 5°C; 2: furan-2-carboxylic acid With ammonium cerium(IV) nitrate in water T=20°C; 7 h;
参考文献
Subrahmanya Bhat; Shivarama Holla
Heterocyclic Communications, 2003 , vol. 9, # 6 p. 625 - 628
反应条件
1: quinoline; copper(II) oxide / 0.33 h / 170 - 180 °C / Neat (no solvent) 2: hydrazine hydrate / ethanol / 2 h / Reflux View Scheme
参考文献
Pilipenko, Arkady S.; Mel'Chin, Vladimir V.; Trushkov, Igor V.; Cheshkov, Dmitry A.; Butin, Alexander V.
Tetrahedron, 2012 , vol. 68, # 2 p. 619 - 627
反应条件
thionyl chloride in benzene Reflux;
参考文献
Gorak; Obushak; Matiichuk; Lytvyn
Russian Journal of Organic Chemistry, 2009 , vol. 45, # 4 p. 541 - 550
反应条件
borane dimethyl sulfide complex in tetrahydrofuran T=50 - 60°C; 2.5 h; Inert atmosphere;
参考文献
ACS Medicinal Chemistry Letters, , vol. 4, # 5 p. 475 - 480
反应条件
hydrogen; palladium on activated charcoal
参考文献
Huang, Qing-Qing; Huang, Min; Nan, Fa-Jun; Ye, Qi-Zhuang
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 24 p. 5386 - 5391
参考文献
Cui, Zining; Li, Ying; Ling, Yun; Huang, Juan; Cui, Jingrong; Wang, Ruiqing; Yang, Xinling
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 12 p. 5576 - 5584
