反应条件
1: 6-chloro-nicotinic acid With tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether T=20°C; 0.25 h; 2: 3,4,5-trimethoxyphenylboronic acid With sodium carbonate in ethylene glycol dimethyl ether; water T=95°C;
参考文献
Coteron, Jose M.; Catterick, David; Castro, Julia; Chaparro, Maria J.; Diaz, Beatriz; Fernandez, Esther; Ferrer, Santiago; Gamo, Francisco J.; Gordo, Mariola; Gut, Jiri; De Las Heras, Laura; Legac, Jennifer; Marco, Maria; Miguel, Juan; Munoz, Vicente; Porras, Esther; De La Rosa, Juan C.; Ruiz, Jose R.; Sandoval, Elena; Ventosa, Pilar; Rosenthal, Philip J.; Fiandor, Jose M.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 16 p. 6129 - 6152