DL-2-氯-2-苯基乙酰氯合成路线 （共 51 条）
参考文献
Upjohn Co.
Patent: US2814624 , 1954 ;
参考文献
Walker, Keith A. M.; Sjogren, Eric B.; Matthews, Thomas R.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 11 p. 1673 - 1679
反应条件
Behandeln der Reaktionsloesung mit wss. Ammoniak und Ammoniumchlorid;
参考文献
Boyle; McKenzie; Mitchell
Chemische Berichte, 1937 , vol. 70, p. 2153,2159
反应条件
1: Et3N / hexane / 2.5 h / Heating
2: Zn, acetic acid / H2O / 24 h / Ambient temperature
3: 71 percent / NBS, benzoyl peroxide / CCl4 / 18 h / Heating
View Scheme
参考文献
Brady, William T.; Agho, Michael O.
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5337 - 5341
反应条件
1: Et3N / hexane / 2.5 h / Heating
2: Zn, acetic acid / H2O / 24 h / Ambient temperature
View Scheme
参考文献
Brady, William T.; Agho, Michael O.
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5337 - 5341
参考文献
Cerecedo; Sherwin
Journal of Biological Chemistry, 1924 , vol. 58, p. 221
反应条件
triethylamine in dichloromethane
T=20°C; 0.25 h;
参考文献
Avalos, Martin; Babiano, Reyes; Cintas, Pedro; Diaz, Jesus; Jimenez, Jose L.; Lopez, Ignacio; Palacios, Juan C.
European Journal of Organic Chemistry, 2004 , # 13 p. 2805 - 2811
反应条件
triethylamine in benzene
Heating;
参考文献
Bentley,R.L.; Suschitzky,H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1976 , p. 1725 - 1734
反应条件
sodium hydroxide in diethyl ether
0 deg C, 1 h, then r.t., 1.5 h;
参考文献
Aoyama; Nakano; Marumo; Uno; Shioiri
Synthesis, 1991 , # 12 p. 1163 - 1167
反应条件
1: Py
2: 195 °C / 13 Torr
View Scheme
参考文献
Takamizawa,A. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 892 - 900
