4-(2-羟基丙烷-2-基)苯酚合成路线 （共 10 条）
反应条件
ammonium chloride; methyllithium in tetrahydrofuran; ice-water; diethyl ether; hexane; ethyl acetate; acetone
参考文献
General Electric Company
Patent: US5990362 A1, 1999 ;
反应条件
chloro-trimethyl-silane in tetrahydrofuran; diethyl ether T=0°C; 2 h; Yields of byproduct given;
参考文献
Rubottom, George M.; Kim, Chong-wan
Journal of Organic Chemistry, 1983 , vol. 48, # 9 p. 1550 - 1552
反应条件
1: With methyllithium in tetrahydrofuran 2: With hydrogenchloride; water pH=4 - 5;
参考文献
AMOREPACIFIC CORPORATION
Patent: WO2007/120012 A1, 2007 ;
Location in patent: Page/Page column 100 ;
WO 2007/120012 A1
反应条件
3,3-dimethyldioxirane in acetone T=25°C; 0.5 h; relative rate; Rate constant;
参考文献
Murray, Robert W.; Gu, Hong
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5673 - 5677
参考文献
Attia,S.Y. et al.
Journal of the American Chemical Society, 1977 , vol. 99, p. 3401 - 3408
反应条件
in tetrahydrofuran T=0 - 20°C;
参考文献
Maruyama, Keisuke; Nakamura, Masaharu; Tomoshige, Shusuke; Sugita, Kazuyuki; Makishima, Makoto; Hashimoto, Yuichi; Ishikawa, Minoru
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 14 p. 4031 - 4036
参考文献
Pospisek,J. et al.
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, p. 142 - 148
反应条件
sulfuric acid T=0 - 20°C;
参考文献
Maruyama, Keisuke; Nakamura, Masaharu; Tomoshige, Shusuke; Sugita, Kazuyuki; Makishima, Makoto; Hashimoto, Yuichi; Ishikawa, Minoru
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 14 p. 4031 - 4036
反应条件
(i) HCl, CH2Cl2, (ii) Et3N; Multistep reaction;
参考文献
Pospisek,J. et al.
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, p. 142 - 148
