4,4-二甲基-3,4-二氢-2H-萘-1-酮合成路线 （共 37 条）
反应条件
1.1: lithium diisopropyl amide / tetrahydrofuran / 5.25 h / 0 °C / Inert atmosphere 1.2: -78 - 20 °C / Inert atmosphere 1.3: 0.5 h / Cooling with ice 2.1: toluene-4-sulfonic acid / toluene / 60 h / Molecular sieve; Reflux; Inert atmosphere; Dean-Stark trap 3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.75 h / -78 °C / Inert atmosphere 4.1: [Ph3PCuCl]4 / tetrahydrofuran / 2 h / Reflux; Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 16 p. 7005 - 7022
反应条件
1: toluene-4-sulfonic acid / toluene / 60 h / Molecular sieve; Reflux; Inert atmosphere; Dean-Stark trap 2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.75 h / -78 °C / Inert atmosphere 3: [Ph3PCuCl]4 / tetrahydrofuran / 2 h / Reflux; Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 16 p. 7005 - 7022
反应条件
1.1: toluene-4-sulfonic acid / benzene / 23 h / Reflux; Inert atmosphere; Dean-Stark apparatus 2.1: lithium diisopropyl amide / tetrahydrofuran / 5.25 h / 0 °C / Inert atmosphere 2.2: -78 - 20 °C / Inert atmosphere 2.3: 0.5 h / Cooling with ice 3.1: toluene-4-sulfonic acid / toluene / 60 h / Molecular sieve; Reflux; Inert atmosphere; Dean-Stark trap 4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.75 h / -78 °C / Inert atmosphere 5.1: [Ph3PCuCl]4 / tetrahydrofuran / 2 h / Reflux; Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 16 p. 7005 - 7022
反应条件
9,10-anthracenedicarbonitrile in acetonitrile 8 h; without isobutene, without 9,10-dicyanoanthracene, other solvents, other time, irradiation; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 111, # 18 p. 7149 - 7155
反应条件
aluminium trichloride
参考文献
Journal of the Chemical Society, , p. 4566 - 4576
反应条件
1: (i) Mg, MeI, (ii) /BRN= 1900390/ 2: (i) SOCl2, (ii) AlCl3, CS2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 37, p. 825 - 836
反应条件
1: (i) Mg, Et2O, (ii) aq. H2SO4 2: (i) 1,1-dimethyl-propyl hydroperoxide, (ii) aq. HIO4 3: (i) PCl5, CS2, (ii) AlCl3, (iii) aq. HCl View Scheme
参考文献
Journal of Organic Chemistry, , vol. 29, # 7 p. 1663 - 1669
反应条件
1: (i) 1,1-dimethyl-propyl hydroperoxide, (ii) aq. HIO4 2: (i) PCl5, CS2, (ii) AlCl3, (iii) aq. HCl View Scheme
参考文献
Journal of Organic Chemistry, , vol. 29, # 7 p. 1663 - 1669
参考文献
Journal of the American Chemical Society, , vol. 69, p. 2322,2324
反应条件
1: 80 percent / AlCl3, Br2 / CH2Cl2 / 70 °C 2: (PPh3)2PdCl2, CuI, Et2NH / 60 °C 3: K2CO3 / methanol / Ambient temperature 4: 64 percent / (PPh3)2PdCl2, CuI, Et2NH / Ambient temperature 5: 1.) NaN(SiMe3)2 / 1.) THF, -78 deg C, 2.) THF, from 0 deg C to RT 6: 1.) t-BuLi, 2.) ZnCl2, 3.) Pd(PPh3)4 View Scheme
参考文献
Johnson; Klein; Gillett; Wang; Song; Pino; Chandraratna
Journal of Medicinal Chemistry, 1995 , vol. 38, # 24 p. 4764 - 4767
