(1S,2S)-(-)-1,2-二苯基乙二胺合成路线 (共 32 条)
反应条件
carbon; triethylamine in tetrahydrofuran T=50°C; 16 h;
参考文献
Alouane, Nacira; Boutier, Audrey; Baron, Cyriella; Vrancken, Emmanuel; Mangeney, Pierre
Synthesis, 2006 , # 5 p. 885 - 889
反应条件
in dichloromethane T=5 - 20°C;
参考文献
Ma, Ting; Fu, Xiao; Kee, Choon Wee; Zong, Lili; Pan, Yuanhang; Huang, Kuo-Wei; Tan, Choon-Hong
Journal of the American Chemical Society, 2011 , vol. 133, # 9 p. 2828 - 2831
反应条件
triethylamine in tetrahydrofuran T=20°C; 12 h; Cooling with ice;
参考文献
Li, Wenjun; Wu, Wenbin; Yu, Feng; Huang, Huicai; Liang, Xinmiao; Ye, Jinxing
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2505 - 2511
反应条件
sodium hydroxide; water in dichloromethane T=0°C; 1.33333 h; Product distribution / selectivity;
参考文献
Bosch, Boris Elmar; Gerhartz, Frank
Patent: US2005/59842 A1, 2005 ;
Location in patent: Page/Page column 5 ;
反应条件
triethylamine in dichloromethane
参考文献
Corey, E. J.; Lee, Duck-Hyung; Sarshar, Sepehr
Tetrahedron: Asymmetry, 1995 , vol. 6, # 1 p. 3 - 6
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 2 h;
参考文献
Hilgraf, Robert; Pfaltz, Andreas
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 1 p. 61 - 77
反应条件
sodium hydroxide; water in dichloromethane T=0°C; 2 h; Product distribution / selectivity;
参考文献
Bosch, Boris Elmar; Gerhartz, Frank
Patent: US2005/59842 A1, 2005 ;
Location in patent: Page/Page column 5 ;
反应条件
triethylamine in tetrahydrofuran T=20°C; 12 h; Cooling with ice;
参考文献
Li, Wenjun; Wu, Wenbin; Yu, Feng; Huang, Huicai; Liang, Xinmiao; Ye, Jinxing
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2505 - 2511
反应条件
sodium hydroxide; water in dichloromethane T=0°C; 2 h; Product distribution / selectivity;
参考文献
EP1375477 A2, ;
Page/Page column 7-8 ;
反应条件
triethylamine in tetrahydrofuran T=20°C; 1 h;
参考文献
Kucherenko, Alexander S.; Siyutkin, Dmitry E.; Nigmatov, Albert G.; Chizhov, Alexander O.; Zlotin, Sergei G.
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 16 p. 3078 - 3086