1: ammonium carbonate / aq. ethanol / 55 - 60 °C 2: aq. NaOH / 72 h / Heating 3: aq. NaOH / dioxane / 12 h / Ambient temperature View Scheme
参考文献
Palacin, Serge; Chin, Donovan N.; Simanek, Eric E.; MacDonald, John C.; Whitesides, George M.; McBride, Mary T.; Palmore, G. Tayhas R.
Journal of the American Chemical Society, 1997 , vol. 119, # 49 p. 11807 - 11816
1: trimethyl-oxo-sulfonium iodide With sodium hydride in tetrahydrofuran; mineral oil 3 h; Inert atmosphereReflux; 2: tetrahydro-pyran-4-one in tetrahydrofuran; mineral oil 2 h; RefluxInert atmosphere;