5-氟-1,3-二甲基尿嘧啶合成路线 （共 17 条）
反应条件
TEA
T=70°C; 0.5 h; di-isopropylethylamine;
参考文献
Visser, W. M. Gerard; Herder, E. Renella; Kanter, Frans J. J. de; Herscheid D. M. Jacobus
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1203 - 1208
反应条件
CsSO4F in acetonitrile
Ambient temperature;
参考文献
Stavber, Stojan; Zupan, Marko
Journal of the Chemical Society, Chemical Communications, 1983 , # 10 p. 563 - 564
反应条件
AcOF in water-d2
Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Visser, W. M. Gerard; Herder, E. Renella; Kanter, Frans J. J. de; Herscheid D. M. Jacobus
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1203 - 1208
反应条件
potassium carbonate
1.) dimethylformamide, room temperature, overnight, 2.) room temperature, 3 d; Yield given. Multistep reaction;
参考文献
Kundu; Schmitz
Journal of Pharmaceutical Sciences, 1982 , vol. 71, # 8 p. 935 - 938
反应条件
in tetradeuterioacetic acid
Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Visser, W. M. Gerard; Herder, E. Renella; Kanter, Frans J. J. de; Herscheid D. M. Jacobus
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1203 - 1208
反应条件
sodium peroxodisulphate in water
T=80°C; 5 h;
参考文献
Itahara, Toshio; Nishino, Akihiro
Chemistry Letters, 1991 , # 12 p. 2203 - 2204
反应条件
Irradiation; MechanismProduct distribution;
参考文献
Savino, Thomas G.; Chenard, Lois Konicki; Swenton, John S.
Tetrahedron Letters, 1983 , vol. 24, # 38 p. 4055 - 4058
