5-[2-氯-5-(三氟甲基)苯基]-2-糠酸合成路线 (共 2 条)
反应条件
potassium hydroxide in ethanol 0.5 h; Reflux;
参考文献
Gorak; Obushak; Matiichuk; Lytvyn
Russian Journal of Organic Chemistry, 2009 , vol. 45, # 4 p. 541 - 550
反应条件
1: 1-amino-2-chloro-5-trifluoromethylbenzene With hydrogenchloride; sodium nitrite T=0 - 5°C; 2: furan-2-carboxylic acid With copper dichloride in water T=20°C; 4 h; Further stages.;
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 182, # 5 p. 1083 - 1091