反应条件
1.1: sodium hydroxide / water / 3.5 h / 90 °C / Inert atmosphere; Darkness 2.1: potassium carbonate / acetone / 24 h / Inert atmosphere; Reflux 3.1: titanium tetrachloride / 20 °C 3.2: 20 °C 4.1: sodium chlorite; potassium dihydrogenphosphate; dihydrogen peroxide / acetonitrile / 20 °C 4.2: 20 °C 5.1: boron tribromide / dichloromethane View Scheme
参考文献
Wei, Jun; Kitada, Shinichi; Stebbins, John L.; Placzek, William; Zhai, Dayong; Wu, Bainan; Rega, Michele F.; Zhang, Ziming; Cellitti, Jason; Yang, Li; Dahl, Russell; Reed, John C.; Pellecchia, Maurizio
Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 8000 - 8011