(S)-2-氨基-5-甲氧基-5-氧代戊酸盐酸盐合成路线 （共 7 条）
反应条件
hydrogenchloride T=20°C; 6 h;
参考文献
Ager, David J.; Babler, Scott; Erickson, Robert A.; Froen, Diane E.; Kittleson, Jeannine; Pantaleone, David P.; Prakash, Indra; Zhi, Ben
Organic Process Research and Development, 2004 , vol. 8, # 1 p. 72 - 85
反应条件
hydrogenchloride 0.00555556 h;
参考文献
Baldwin, Jack E.; North, Michael; Flinn, Anthony; Moloney, Mark G.
Tetrahedron, 1989 , vol. 45, # 5 p. 1453 - 1464
反应条件
triethylamine in 1,4-dioxane; water 4 h; Ambient temperature;
参考文献
El Marini; Roumestant; Viallefont; Razafindramboa; Bonato; Follet
Synthesis, 1992 , # 11 p. 1104 - 1108
反应条件
sulfuric acid in tetrahydrofuran 18 h; Ambient temperature;
参考文献
Baldwin, Jack E.; North, Michael; Flinn, Anthony; Moloney, Mark G.
Tetrahedron, 1989 , vol. 45, # 5 p. 1453 - 1464
反应条件
1.1: triethylamine / N,N-dimethyl-formamide 1.2: 24 h 2.1: pyridine; 4-(N,N-dimethlyamino)pyridine; di-tert-butyl dicarbonate / 24 h 3.1: water; sodium hydroxide / acetone / 1.5 h / -2 °C 3.2: pH 4 View Scheme
参考文献
Cui, Hong-Kui; Guo, Ye; He, Yao; Wang, Feng-Liang; Chang, Hao-Nan; Wang, Yu-Jia; Wu, Fang-Ming; Tian, Chang-Lin; Liu, Lei
Angewandte Chemie - International Edition, 2013 , vol. 52, # 36 p. 9558 - 9562
Angew. Chem., 2013 , vol. 125, # 36 p. 9737 - 9741,5
反应条件
1: 95 percent / Et3N / dioxane; H2O / 4 h / Ambient temperature 2: Et3N / tetrahydrofuran / 0.5 h / -10 °C 3: NaBH4 / H2O; tetrahydrofuran / 4 h / Ambient temperature View Scheme
参考文献
El Marini; Roumestant; Viallefont; Razafindramboa; Bonato; Follet
Synthesis, 1992 , # 11 p. 1104 - 1108
参考文献
Voelter,W. et al.
Monatshefte fuer Chemie, 1974 , vol. 105, p. 1110 - 1135
