5,5-二甲基-二氢-呋喃-2-酮合成路线 （共 98 条）
反应条件
phosphoric acid; methylmagnesium bromide in diethyl ether; ethyl acetate; benzene
参考文献
Bristol-Myers Squibb Co.
Patent: US5648385 A1, 1997 ;
反应条件
sulfuric acid in methyl-magnesium iodide; water
参考文献
Bigge; Christopher F.; Hays; Sheryl J.; Johnson; Graham; Novak; Perry M.; Ortwine; Daniel F.
Patent: US5071853 A1, 1991 ;
反应条件
dipyridinium dichromate in N,N-dimethyl-formamide T=20°C; 3 h;
参考文献
Martin, David Diez; Marcos, Isidro S.; Basabe, Pilar; Romero, Ricardo E.; Moro, Rosalina F.; Lumeras, Wenceslao; Rodriguez, Lucena; Urones, Julio G.
Synthesis, 2001 , # 7 p. 1013 - 1022
反应条件
paraformaldehyde; rhodium(III) chloride trihydrate in benzene
反应条件
C12H16BN6O6S3(1-)*Cu(1+) in dichloromethane T=20°C; Inert atmosphere; chemoselective reaction;
参考文献
Martin, Carmen; Belderrain, Tomas R.; Perez, Pedro J.
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 22 p. 4777 - 4781
反应条件
chloro-trimethyl-silane; sodium iodide in acetonitrile T=60°C;
参考文献
Piva, Olivier
Tetrahedron, 1994 , vol. 50, # 48 p. 13687 - 13696
反应条件
in diethyl ether T=20°C;
参考文献
Wyeth
Patent: US2005/215539 A1, 2005 ;
Location in patent: Page/Page column 35 ;
US 20050215539 A1
反应条件
potassium permanganate; water; copper(II) sulfate in dichloromethane 1.) reflux, 5 min, 2.) RT, 4 h;
参考文献
Baskaran, Sundarababu; Islam, Imadul; Vankar, Padma S.; Chandrasekaran, Srinivasan
Journal of the Chemical Society, Chemical Communications, 1990 , # 23 p. 1670 - 1671
反应条件
in tetrahydrofuran; benzene T=0°C; 3 h;
参考文献
Citron, Christian A.; Rabe, Patrick; Dickschat, Jeroen S.
Journal of Natural Products, 2012 , vol. 75, # 10 p. 1765 - 1776
反应条件
3 A molecular sieve; pyridinium chlorochromate in dichloromethane 3.5 h; Heating;
参考文献
Baskaran, S.; Chandrasekaran, S.
Tetrahedron Letters, 1990 , vol. 31, # 19 p. 2775 - 2778
