3,5-二溴-2-羟基苯甲酸合成路线 （共 79 条）
参考文献
Dahmer
Justus Liebigs Annalen der Chemie, 1904 , vol. 333, p. 353
反应条件
phosphorus trichoride in chlorobenzene 3 h; Heating;
参考文献
Waisser, Karel; Hladuvkova, Jana; Gregor, Jiri; Rada, Tomas; Kubicova, Lenka; Klimesova, Vera; Kaustova, Jarmila
Archiv der Pharmazie, 1998 , vol. 331, # 1 p. 3 - 6
反应条件
1: PCl3 / chlorobenzene / 0.25 h / Heating 2: chlorobenzene / 3 h / Heating View Scheme
参考文献
Coburn; Batista; Evans; Genco
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1245 - 1249
参考文献
Pilyugin; Sapozhnikov; Sapozhnikova
Russian Journal of General Chemistry, 2004 , vol. 74, # 5 p. 738 - 743
反应条件
sulfuric acid; bromine; copper(II) sulfate 15 h;
参考文献
Renneberg, Bernd; Kellner, Michael; Laatsch, Hartmut
Liebigs Annalen der Chemie, 1993 , # 8 p. 847 - 852
参考文献
Farinholt; Stuart; Twiss
Journal of the American Chemical Society, 1940 , vol. 62, p. 1237,1240
反应条件
potassium carbonate in N,N-dimethyl-formamide T=25°C; 48 h;
参考文献
ASTRAZENECA AB
Patent: WO2006/121390 A2, 2006 ;
Location in patent: Page/Page column 84-85 ;
WO 2006/121390 A2
反应条件
potassium carbonate in acetone 12 h; Heating;
参考文献
Laatsch, Hartmut; Pudleiner, Heinz
Liebigs Annalen der Chemie, 1989 , p. 863 - 882
反应条件
1: hydrogen chloride 2: potassium hydroxide; methanol / 110 - 120 °C View Scheme
参考文献
Peratoner
Gazzetta Chimica Italiana, 1886 , vol. 16, p. 421
反应条件
T=220 - 230°C; im geschlossenen Rohr;
参考文献
Peratoner
Gazzetta Chimica Italiana, 1886 , vol. 16, p. 402
