2,3-二(氯甲基)-1,4-二氢萘-1,4-二酮合成路线 （共 9 条）
反应条件
hydrogenchloride in acetic acid
参考文献
Lin; Antonini; Cosby; Sartorelli
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 813 - 815
参考文献
Thomson
Journal of the Chemical Society, 1953 , p. 1196,1198
反应条件
tetra(n-butyl)ammonium hydroxide in water; toluene 1.) 1 h, 2.) r.t., irradiation, 48 h;
参考文献
Vanelle, Patrice; Terme, Thierry; Maldonado, Jose; Crozet, Michel P.; Giraud, Luc
Synlett, 1998 , # 10 p. 1067 - 1068
反应条件
1: 32 percent / tetrabutylammonium hydroxide / toluene; H2O / 1.) 1 h, 2.) r.t., irradiation, 0.5 h 1 2: 65 percent / tetrabutylammonium hydroxide, nitroethane / toluene; H2O / 1.) 1 h, 2.) r.t., irradiation, 24 h View Scheme
参考文献
Vanelle, Patrice; Terme, Thierry; Maldonado, Jose; Crozet, Michel P.; Giraud, Luc
Synlett, 1998 , # 10 p. 1067 - 1068
反应条件
tetra(n-butyl)ammonium hydroxide in water; toluene 1.) 1 h, 2.) r.t., irradiation, 48 h;
参考文献
Vanelle, Patrice; Terme, Thierry; Maldonado, Jose; Crozet, Michel P.; Giraud, Luc
Synlett, 1998 , # 10 p. 1067 - 1068
反应条件
tetra(n-butyl)ammonium hydroxide in water; toluene 1.) 1 h, 2.) r.t., irradiation, 48 h;
参考文献
Vanelle, Patrice; Terme, Thierry; Maldonado, Jose; Crozet, Michel P.; Giraud, Luc
Synlett, 1998 , # 10 p. 1067 - 1068
反应条件
water in 1,4-dioxane
24 h; Heating;
参考文献
Lin; Antonini; Cosby; Sartorelli
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 813 - 815
反应条件
1: 40 percent / H2O / dioxane / 24 h / Heating
2: 66 percent / CHCl3 / 24 h / Heating
View Scheme
参考文献
Lin; Antonini; Cosby; Sartorelli
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 813 - 815
反应条件
1: 40 percent / H2O / dioxane / 24 h / Heating
2: 1.37 g / CHCl3 / 72 h / Heating
View Scheme
参考文献
Lin; Antonini; Cosby; Sartorelli
Journal of Medicinal Chemistry, 1984 , vol. 27, # 6 p. 813 - 815
