2-氟-4-溴硝基苯合成路线

参考文献

Schlosser, Manfred; Ginanneschi, Assunta; Leroux, Frederic
European Journal of Organic Chemistry, 2006 , # 13 p. 2956 - 2969

321-23-32-氟-4-溴硝基苯

5228-61-55-溴-2-硝基苯胺

参考文献

Sessions, E. Hampton; Smolinski, Michael; Wang, Bo; Frackowiak, Bozena; Chowdhury, Sarwat; Yin, Yan; Chen, Yen Ting; Ruiz, Claudia; Lin, Li; Pocas, Jennifer; Schroeter, Thomas; Cameron, Michael D.; LoGrasso, Philip; Feng, Yangbo; Bannister, Thomas D.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 6 p. 1939 - 1943

321-23-32-氟-4-溴硝基苯

1038408-35-3

参考文献

GLAXOSMITHKLINE LLC; BOTYANSZKI, Janos; DICKERSON, Scott Howard; LEIVERS, Martin Robert; LI, Xiaofei; MCFADYEN, Robert Blount; REDMAN, Aniko Maria; SHOTWELL, John Bradford; XUE, Jianjun
Patent: WO2012/174312 A2, 2012 ;
WO 2012/174312 A2

321-23-32-氟-4-溴硝基苯+

124-41-4甲醇钠

103966-66-15-溴-2-硝基苯甲醚

参考文献

ABBOTT GMBH and CO. KG
Patent: WO2006/40182 A1, 2006 ;
Location in patent: Page/Page column 168 ;
WO 2006/040182 A1

67-56-1甲醇+

321-23-32-氟-4-溴硝基苯+

124-41-4甲醇钠

103966-66-15-溴-2-硝基苯甲醚

参考文献

Kuntz, Kevin; Uehling, David Edward; Waterson, Alex Gregory; Emmitte, Kyle Allen; Stevens, Kirk; Shotwell, John Brad; Smith, Stephon Cornell; Nailor, Kristen E.; Salovich, James M.; Wilson, Brian John; Cheung, Mui; Mook, Robert Anthony; Baum, Erich W.; Moorthy, Ganesh
Patent: US2008/300242 A1, 2008 ;
Location in patent: Page/Page column 137-138 ;
US 20080300242 A1

67-56-1甲醇+

321-23-32-氟-4-溴硝基苯

103966-66-15-溴-2-硝基苯甲醚

参考文献

Yin, Yan; Cameron, Michael D.; Lin, Li; Khan, Susan; Schroeter, Thomas; Grant, Wayne; Pocas, Jennifer; Chen, Yen Ting; Schuerer, Stephan; Pachori, Alok; Lograsso, Philip; Feng, Yangbo
ACS Medicinal Chemistry Letters, 2010 , vol. 1, # 4 p. 175 - 179

321-23-32-氟-4-溴硝基苯

256935-99-6

参考文献

Schlosser, Manfred; Ginanneschi, Assunta; Leroux, Frederic
European Journal of Organic Chemistry, 2006 , # 13 p. 2956 - 2969

321-23-32-氟-4-溴硝基苯

1233145-65-7

参考文献

SANOFI
Patent: US2012/277220 A1, 2012 ;

321-23-32-氟-4-溴硝基苯

305790-48-16-溴-1-甲基-1,3-二氢-2H-苯并咪唑-2-酮

参考文献

MERCK SHARP and DOHME CORP.; DUDKIN, Vadim; FRALEY, Mark, E.; ARRINGTON, Kenneth, L.; LAYTON, Mark, E.; RODZINAK, Kevin, J.; PERO, Joseph, E.; REIF, Alexander, J.
Patent: WO2012/21382 A1, 2012 ;
WO 2012/021382 A1

321-23-32-氟-4-溴硝基苯+

7486-35-3三丁基乙烯基锡

197777-90-5

参考文献

ABBOTT GMBH and CO. KG
Patent: WO2006/40182 A1, 2006 ;
Location in patent: Page/Page column 165-166 ;
WO 2006/040182 A1