alpha-氰基异戊酸乙基酯合成路线 （共 24 条）
参考文献
Nielsen et al.
Acta Chemica Scandinavica (1947-1973), 1959 , vol. 13, p. 1943,1951
反应条件
1: concentrated sulfuric acid / 100 °C 2: methyl acetate 3: aqueous ether; nitrogen oxides View Scheme
参考文献
Fischer,E.; Brauns
Chemische Berichte, 1914 , vol. 47, p. 3184
Chem. Zentralbl., 1914 , vol. 85, # II p. 981
反应条件
Durch Kochen des erhaltenen Azids mit Aethanol und Hydrolyse des Reaktionsprodukts mit wss. HCl bei Siedetemperatur;
参考文献
Gagnon; Gaudry; King
Journal of the Chemical Society, 1944 , p. 13
反应条件
1: (i) Na, toluene, (ii) ClO3F 2: aq. NaOH View Scheme
参考文献
Gershon,H. et al.
Journal of Medicinal Chemistry, 1967 , vol. 10, p. 536 - 541
反应条件
(i) EtOH, (ii) ClO3F; Multistep reaction;
参考文献
Gershon,H. et al.
Journal of Medicinal Chemistry, 1967 , vol. 10, p. 536 - 541
反应条件
(i) Na, toluene, (ii) ClO3F; Multistep reaction;
参考文献
Gershon,H. et al.
Journal of Medicinal Chemistry, 1967 , vol. 10, p. 536 - 541
反应条件
potassium hydroxide; ethanol
参考文献
Eberson,L.; Nilsson,S.
Acta Chemica Scandinavica (1947-1973), 1968 , vol. 22, # 8 p. 2453 - 2461
反应条件
1: (i) EtOH, (ii) ClO3F 2: aq. HCl View Scheme
参考文献
Gershon,H. et al.
Journal of Medicinal Chemistry, 1967 , vol. 10, p. 536 - 541
反应条件
1.1: ethanol; potassium / 1 h / 20 °C / Inert atmosphere 1.2: 9 h / Inert atmosphere; Reflux 2.1: sulfuric acid / water / 16 h / 160 °C 2.2: 0.75 h / 50 °C 3.1: sulfuric acid / ethanol / 24 h / Reflux View Scheme
参考文献
China PetroleumandChemical Corporation; Beijing Research Institute of Chemical Industry, China Petroleum and Chemical Corporation
Patent: EP2399902 A1, 2011 ;
反应条件
1: NaBH4 / methanol 2: aq. NaOH / ethanol 3: diethyl ether View Scheme
参考文献
Mori,K. et al.
Tetrahedron, 1970 , vol. 26, p. 2821 - 2824
