1-甲基-4-苯基乙炔苯合成路线 （共 165 条）
反应条件
potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(I) bromide in N,N-dimethyl-formamide T=140 - 145°C; Sonogashira type cross-coupling reaction; 20 h; Inert atmosphere;
参考文献
Zhang, Jing; Crossed, Dakovic Marijana; Popovic, Zora; Wu, Haihong; Liu, Ye
Catalysis Communications, 2012 , vol. 17, p. 160 - 163
反应条件
copper(l) iodide; potassium carbonate; triphenylphosphine in dimethyl sulfoxide T=90°C; 24 h; Inert atmosphere;
参考文献
Li, Tingyi; Sun, Peng; Yang, Hailong; Zhu, Yan; Yan, Hong; Lu, Linhua; Mao, Jincheng
Tetrahedron, 2012 , vol. 68, # 32 p. 6413 - 6419
反应条件
KOC(O)Ph; triphenylphosphine; copper(l) chloride in 1,3-dimethyl-imidazolidin-2-one T=120°C; Sila-Sonogashira-Hagihara cross-coupling reaction; 12 h; Inert atmosphere;
参考文献
Ihara, Hideki; Ueda, Akinori; Suginome, Michinori
Chemistry Letters, 2011 , vol. 40, # 9 p. 972 - 974
反应条件
[PdCl{[(η5-C5H5)]Fe[(η5-C5H3)-N2C4H2-Cl]}(C3N2H2)(C6H3-2C3H7)2]; caesium acetate in N,N-dimethyl acetamide T=120°C; Sonogashira Cross-Coupling; 12 h; Inert atmosphere;
参考文献
Xu, Chen; Lou, Xin-Hua; Wang, Zhi-Qiang; Fu, Wei-Jun
Transition Metal Chemistry, 2012 , vol. 37, # 6 p. 519 - 523
反应条件
copper(l) iodide; 8-hydroxy-quinoline; sodium salt of phosphorous acid in ethanol T=80°C; Suzuki coupling; 24 h;
参考文献
Wang, Shihua; Wang, Min; Wang, Lei; Wang, Bo; Li, Pinhua; Yang, Jin
Tetrahedron, 2011 , vol. 67, # 26 p. 4800 - 4806
反应条件
copper(l) iodide; potassium carbonate; NiCl2((PPh3)P)2 in 1,4-dioxane; water Sonogashira-Hagihara reaction; 4 h; Heating;
参考文献
Imura, Yumi; Shimojuh, Naoya; Kawano, Yuhta; Togo, Hideo
Tetrahedron, 2010 , vol. 66, # 19 p. 3421 - 3426
反应条件
diisopropyl-(9-ethyl-9H-fluoren-9-yl)phosphane*HBF4; copper(l) iodide in dimethyl sulfoxide T=120°C; Sonogashira coupling reaction; 16 h;
参考文献
Jin, Myung-Jong; Lee, Dong-Hwan
Angewandte Chemie - International Edition, 2010 , vol. 49, # 6 p. 1119 - 1122
反应条件
C18H19N3O2Pd; caesium carbonate in N,N-dimethyl-formamide T=140°C; 1 h;
参考文献
Reddy, Police Vishnuvardhan; Srinivas, Pottabathula; Annapurna, Manne; Bhargava, Suresh; Wagler, Jorg; Mirzadeh, Nedaossadat; Kantam, Mannepalli Lakshmi
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 705 - 710
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in dimethyl sulfoxide T=90°C; 12 h;
参考文献
Pyo, Ayoung; Kim, Ji Dang; Choi, Hyun Chul; Lee, Sunwoo
Journal of Organometallic Chemistry, 2013 , vol. 724, p. 271 - 274
反应条件
tetra-n-butylammonium acetate; palladium(II) complex in 1-methyl-pyrrolidin-2-one T=110°C; Sonogashira coupling; 1 h;
参考文献
Hill, Lensey L.; Smith, Joanna M.; Brown, William S.; Moore, Lucas R.; Guevera, Paul; Pair, Emily S.; Porter, Jake; Chou, Joe; Wolterman, Christopher J.; Craciun, Raluca; Dixon, David A.; Shaughnessy, Kevin H.
Tetrahedron, 2008 , vol. 64, # 29 p. 6920 - 6934
